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Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201800335
Abstract: The encapsulation of mRNA in nanosystems as gene vaccines for immunotherapy purposes has experienced an exponential increase in recent years. Despite the many advantages envisaged within these approaches, their application in clinical treatments is still…
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Keywords:
delivery system;
presenting cells;
mrna delivery;
system targeting ... See more keywords
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Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202101190
Abstract: The growing enthusiasm for cancer immunotherapies and adoptive cell therapies has prompted increasing interest in biomaterials development mimicking natural antigen-presenting cells (APCs) for T-cell expansion. In contrast to conventional bottom-up approaches aimed at layering synthetic…
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Keywords:
intracellular hydrogelation;
dendritic cells;
antigen;
antigen presenting ... See more keywords
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Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202249980
Abstract: Antigen presenting cells (APCs) are critical cells bridging innate and adaptive immune responses by taking up, processing, and presenting antigens to naïve T cells. At steady state, APCs thus control both tissue homeostasis and the…
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Keywords:
antigen presenting;
presenting cells;
specific antigen;
tissue specific ... See more keywords
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Published in 2022 at "Glia"
DOI: 10.1002/glia.24257
Abstract: The plastic potential of Schwann cells (SCs) is increasingly recognized to play a role after nerve injury and in diseases of the peripheral nervous system. In addition, reports on the interaction between SCs and immune…
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Keywords:
repair related;
antigen presenting;
schwann cells;
presenting cells ... See more keywords
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Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25514
Abstract: Polio eradication has been achieved in the world except for three countries due to the widespread use of the inactivated poliovirus vaccine (IPV) and the live‐attenuated oral poliovirus vaccine. Following polio eradication, the IPV would…
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Keywords:
vaccine;
antigen presenting;
human antigen;
polio vaccine ... See more keywords
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Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1736-6_11
Abstract: CD4+ T follicular helper (Tfh) cells are essential for initiating and regulating efficient humoral responses in secondary lymphoid organs. Tfh polarization and differentiation is driven by multiple stimuli delivered by antigen presenting cells (APCs). APCs…
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Keywords:
human tfh;
identification antigen;
tfh;
biology ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7474-0_10
Abstract: In vivo, B cells are often activated by antigens that are displayed on the surface of antigen-presenting cells (APCs). Binding of membrane-associated antigens to the B cell receptor (BCR) causes rapid cytoskeleton-dependent changes in the…
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Keywords:
imaging interactions;
bcr;
presenting cells;
model antigens ... See more keywords
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Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.11.038
Abstract: Biomimetic materials that target the immune system and generate an anti-tumor responses hold promise in augmenting cancer immunotherapy. These synthetic materials can be engineered and optimized for their biodegradability, physical parameters such as shape and…
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Keywords:
melanoma;
biomimetic biodegradable;
blockade;
artificial antigen ... See more keywords
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Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00993
Abstract: Immunotherapy is deemed one of the most powerful therapeutic approaches to treat cancer. However, limited response and tumor specificity are still major challenges to address. Herein, mannosylated polycations targeting mannose receptor- are developed as vectors…
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Keywords:
cell;
antigen presenting;
activation;
presenting cells ... See more keywords
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Published in 2022 at "Nano Letters"
DOI: 10.1021/acs.nanolett.2c00819
Abstract: Autoimmune diseases and in particular type 1 diabetes rely heavily on treatments that target the symptoms rather than prevent the underlying disease. One of the barriers to better therapeutic strategies is the inability to detect…
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Keywords:
desensitization autoreactive;
antigen presenting;
type diabetes;
artificial antigen ... See more keywords
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Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.1c04363
Abstract: Ineffective antigen cross-presentation in the tumor microenvironment compromises the generation of antitumor immune responses. Radiotherapy-radiodynamic therapy (RT-RDT) with nanoscale metal-organic frameworks (nMOFs) induces robust adaptive immune responses despite modest activation of canonical antigen presenting dendritic…
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Keywords:
canonical antigen;
immune responses;
antigen;
radiotherapy radiodynamic ... See more keywords