ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2993-2
Abstract: Cardiovascular disease (CVD) is the leading cause of mortality in the world, with most CVD-related deaths resulting from myocardial infarction or stroke. The main underlying cause of thrombosis and cardiovascular events is atherosclerosis, an inflammatory… read more here.
Keywords: auto antigen; antigen targeted; aldh4a1 atherosclerosis; antibody ... See more keywords
Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221107113
Abstract: Purpose: Adoptively transferred, ex vivo expanded multi-antigen-targeted T cells (multiTAA-T) represent a new, potentially effective, and nontoxic therapeutic approach for patients with breast cancer (BC). In this first-in-human trial, we investigated the safety and clinical… read more here.
Keywords: antigen targeted; multitaa cells; breast cancer; multi antigen ... See more keywords