Structure‐based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae
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DOI: 10.1002/2211-5463.12267
Abstract: Effective vaccines are urgently needed to combat gonorrhea, a common sexually transmitted bacterial infection, for which treatment options are diminishing due to rapid emergence of antibiotic resistance. We have used a rational approach to the… read more here.
Keywords: neisseria gonorrhoeae; ferritin nanoparticle; antigenic peptides; structure ... See more keywords
Identification of potential antigenic peptides of Brucella through proteome and peptidome
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DOI: 10.1002/vms3.1048
Abstract: Abstract Background Brucellosis, caused by Brucella spp., is a major zoonotic public health threat. Although several Brucella vaccines have been demonstrated for use in animals, Brucella spp. can cause human infection and to date, there… read more here.
Keywords: potential antigenic; antigenic peptides; proteome peptidome; brucella proteome ... See more keywords
Construction and immunological evaluation of hepatitis B virus core virus-like particles containing multiple antigenic peptides of respiratory syncytial virus.
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DOI: 10.1016/j.virusres.2021.198410
Abstract: Respiratory syncytial virus (RSV) infection causes severe disease in the lower respiratory tract of infants and young children. Currently, no licensed vaccine is available. In this study, we generated the chimeric virus-like particles (tHBc/FE1E2, tHBc/FE1E2/M282-90… read more here.
Keywords: thbc fe1e2; virus; fe1e2 m282; antigenic peptides ... See more keywords
Nuclear processing of nascent transcripts determines synthesis of full-length proteins and antigenic peptides
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DOI: 10.1093/nar/gky1296
Abstract: Abstract Peptides presented on major histocompatibility (MHC) class I molecules form an essential part of the immune system's capacity to detect virus-infected or transformed cells. Earlier works have shown that pioneer translation peptides (PTPs) for… read more here.
Keywords: full length; length proteins; translation; synthesis full ... See more keywords
Tumour‐associated antigenic peptides are present in the HLA class I ligandome of cancer cell line derived extracellular vesicles
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DOI: 10.1111/imm.13471
Abstract: The recent success of monoclonal antibody checkpoint inhibitor therapies that enhance the ability of CD8+ T cells to detect cancer‐related antigenic peptides has refocused the need to fully understand the repertoire of peptides being presented… read more here.
Keywords: cell; antigenic peptides; associated antigenic; tumour associated ... See more keywords
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Chronic Disease"
DOI: 10.1177/20406223211037830
Abstract: Background: Therapeutic treatment options for chronic autoimmune disorders such as multiple sclerosis (MS) rely largely on the use of non-specific immunosuppressive drugs, which are not able to cure the disease. Presently, approaches to induce antigen-specific… read more here.
Keywords: eae tolerogenic; pegylated antigenic; disease; antigenic peptides ... See more keywords