Discovery of trans-3,4,4'-trihydroxystilbene as new lead vasorelaxant agent for antihypertensive drug development.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119560
Abstract: AIMS The structure-vasorelaxant activity relationships (SARs) assessment in previous study has found that trans-3,4,4'-trihydroxystilbene (344OH) could potentially act as a vasorelaxing agent with demonstration of over 2-fold maximal relaxation (Rmax) compared to its analogue, resveratrol.… read more here.
Keywords: drug development; antihypertensive drug; study; drug ... See more keywords
THE IMPACT OF NON-ADHERENCE TO ANTIHYPERTENSIVE DRUG THERAPY
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)32295-8
Abstract: Medication non-adherence is a major healthcare barrier, especially among diseases that are largely asymptomatic such as hypertension. The impact of poor medication adherence ranges from patient specific adverse health outcomes to broader strains on health… read more here.
Keywords: impact non; adherence; non adherence; antihypertensive drug ... See more keywords
Crystal Forms of the Antihypertensive Drug Irbesartan: A Crystallographic, Spectroscopic, and Hirshfeld Surface Analysis Investigation
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c00545
Abstract: The design of new pharmaceutical solids with improved physical and chemical properties can be reached through in-detail knowledge of the noncovalent intermolecular interactions between the molecules in the context of crystal packing. Although crystallization from… read more here.
Keywords: compound; antihypertensive drug; analysis; forms antihypertensive ... See more keywords
Observational study and participant-level meta-analysis on antihypertensive drug treatment-related cardiovascular risk
Sign Up to like & getrecommendations! Published in 2017 at "Hypertension Research"
DOI: 10.1038/hr.2017.60
Abstract: Although antihypertensive therapy reduces cardiovascular risk, individuals who are treated with antihypertensive medication generally have a worse prognosis for cardiovascular disease than untreated people. We recently evaluated the impact of conventional blood pressure level based… read more here.
Keywords: treatment; antihypertensive drug; blood pressure; blood ... See more keywords
Tight control of blood pressure in pregnant women with nonsevere hypertension: expectations for decreasing adverse maternal and fetal pregnancy outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension Research"
DOI: 10.1038/s41440-022-00881-9
Abstract: It has been controversial regarding blood pressure (BP) levels at which antihypertensive drug therapy should be started in women with hypertensive disorders of pregnancy (HDP), which includes chronic hypertension (CH) as well as hypertension occurring… read more here.
Keywords: pregnant women; antihypertensive drug; therapy; pregnancy ... See more keywords
Assessment of the genotoxic effects of antihypertensive drug active ingredient indapamide in human lymphocytes
Sign Up to like & getrecommendations! Published in 2022 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2022.2026375
Abstract: Abstract Hypertension is the most common cardiovascular disease and is also known as high blood pressure. The large majority of hypertensive patients need long-term administration of antihypertensive agents. Indapamide is an orally administered diuretic antihypertensive… read more here.
Keywords: genotoxic effects; antihypertensive drug; drug; genotoxic ... See more keywords
Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Age and ageing"
DOI: 10.1093/ageing/afab192
Abstract: BACKGROUND translation of the available evidence concerning primary cardiovascular prevention into clinical guidance for the heterogeneous population of older adults is challenging. With this review, we aimed to give an overview of the thresholds and… read more here.
Keywords: drug therapy; antihypertensive drug; targets antihypertensive; prevention ... See more keywords
ANTIHYPERTENSIVE DRUG TREATMENT DISCONTINUATION IN PATIENTS UNDERGOING ORTHOPEDIC SURGERY. IS IT SAFE?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000539393.04828.17
Abstract: Objective: High blood pressure levels represent a common reason for postponing a scheduled surgery and are usually based on in hospital blood pressure (BP) measurements. Stress and anxiety of surgery represents a significant factor that… read more here.
Keywords: surgery; drug treatment; treatment; antihypertensive drug ... See more keywords
BLOOD PRESSURE VARIABILITY ASSESSED WITH OFFICE, HOME AND AMBULATORY MEASUREMENTS BEFORE AND AFTER ANTIHYPERTENSIVE DRUG TREATMENT: THE REVERENT TRIAL
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000836360.59061.4d
Abstract: Objective: Blood pressure (BP) variability (BPV) can be assessed using office (OBP), home (HBP) and ambulatory BP (ABP) measurements. In this analysis BPV indices derived using all the three methods were compared before and after… read more here.
Keywords: antihypertensive drug; bpv; variability; abp ... See more keywords
IMPACT OF THE COVID-19 PANDEMIC ON THE INITIATION OF ANTIHYPERTENSIVE DRUG THERAPY IN FRANCE
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837188.24321.76
Abstract: Objective: The objective was to analyze time-trends in the rates of patients who had at least one reimbursement of an antihypertensive drug without reimbursement in the past 12 month for each year from 2017 to… read more here.
Keywords: antihypertensive drug; france; initiation antihypertensive; age ... See more keywords
Antihypertensive Drug Deintensification and Recurrent Falls in Long‐Term Care
Sign Up to like & getrecommendations! Published in 2018 at "Health Services Research"
DOI: 10.1111/1475-6773.13074
Abstract: OBJECTIVE To examine the relationship between antihypertensive drug deintensification and recurrent falls in long-term care. DATA SOURCES/SETTINGS Department of Veterans Affairs (VA) inpatient, outpatient, and purchased care data, Minimum Data Set assessments from VA nursing… read more here.
Keywords: deintensification; antihypertensive drug; drug deintensification; care ... See more keywords