Synthesis, characterization, and antileukemic activity of new water-soluble analogs of prodimin
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DOI: 10.1007/s11172-019-2435-1
Abstract: Two new compounds from the class of bis(3-halopropionyl)amides were synthesized by the reaction of 3-halopropionyl chloride with N,N′-dimethylethylenediamine. These structural analogs of prodimin, a water insoluble anticancer drug, are soluble in water, which significantly expands… read more here.
Keywords: analogs prodimin; antileukemic activity; activity new; water ... See more keywords
Insights into Asparaginase from Endophytic Fungus Lasiodiplodia theobromae: Purification, Characterization and Antileukemic Activity
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DOI: 10.3390/ijerph19020680
Abstract: Endobiotic fungi are considered as a reservoir of numerous active metabolites. Asparaginase is used as an antileukemic drug specially to treat acute lymphoblastic leukaemia. The presented study aims to optimize the media conditions, purify, characterize,… read more here.
Keywords: asparaginase; antileukemic activity; asparaginase showed; purified asparaginase ... See more keywords