3D-QSAR, docking and ADMET properties of aurone analogues as antimalarial agents
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e03580
Abstract: The development of multi-resistant strains of plasmodium parasite has become a global problem, therefore, the discovery of new antimalarial agents is the only available solution. In order to improve and propose new compounds with antimalarial… read more here.
Keywords: qsar docking; docking admet; admet properties; antimalarial agents ... See more keywords
A novel class of fast‐acting antimalarial agents: Substituted 15‐membered azalides
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15292
Abstract: Efficacy of current antimalarial treatments is declining as a result of increasing antimalarial drug resistance, so new and potent antimalarial drugs are urgently needed. Azithromycin, an azalide antibiotic, was found useful in malaria therapy, but… read more here.
Keywords: antimalarial agents; acting antimalarial; class fast; fast acting ... See more keywords
FRI0198 ANTIMALARIAL AGENTS DIMINISH WHILE METHOTREXATE, AZATHIOPRINE AND MYCOPHENOLIC ACID INCREASE BAFF LEVELS IN SYSTEMIC LUPUS ERYTHEMATOSUS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6414
Abstract: Background: Elevated levels of the B cell activating cytokine BAFF (also known as BLyS) have been associated with active systemic lupus erythematosus (SLE), and the anti-BAFF monoclonal antibody belimumab has been approved as an add-on… read more here.
Keywords: azathioprine mycophenolic; methotrexate azathioprine; antimalarial agents; baff ... See more keywords
Ferrocene Derivatives as New Generation of Antimalarial Agents: Opportunity or Illusion?
Sign Up to like & getrecommendations! Published in 2023 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026623666230228153114
Abstract: Despite significant scientific progress over the last two decades, malaria remains a global burden that causes thousands of deaths every year. In the absence of effective and practical preventive measures, the only current option for… read more here.
Keywords: new generation; chemistry; antimalarial agents; drug ... See more keywords