Development of fluorinated nicotinonitriles and fused candidates as antimicrobial, antibiofilm, and enzyme inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200040
Abstract: The antimicrobial assessments of two new series of nicotinonitriles and pyrido[2,3-d]pyrimidines were performed using amoxicillin and nystatin as reference standards. Outstanding antifungal activities were achieved by some target compounds; for instance, compounds 7 and 9… read more here.
Keywords: antimicrobial antibiofilm; candidates antimicrobial; fluorinated nicotinonitriles; development fluorinated ... See more keywords
Assessment of alpha glucosidase inhibitors produced from endophytic fungus Alternaria destruens as antimicrobial and antibiofilm agents
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-05145-3
Abstract: Diabetes is considered as a major health concern worldwide and patients with diabetes are at high risk for infectious diseases. Therefore, α-glucosidase inhibitors possessing antibacterial activity along with the ability to inhibit biofilms would be… read more here.
Keywords: endophytic fungus; antimicrobial antibiofilm; alternaria destruens; glucosidase inhibitors ... See more keywords
Antimicrobial and antibiofilm activity of the EeCentrocin 1 derived peptide EC1-17KV via membrane disruption
Sign Up to like & getrecommendations! Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.102775
Abstract: Background The antibiotic resistance and biofilm formation of pathogenic microbes exacerbate the difficulties of anti-infection therapy in the clinic. The structural modification of antimicrobial peptides (AMP) is an effective strategy to develop novel anti-infective agents.… read more here.
Keywords: antimicrobial antibiofilm; ec1 17kv; membrane; bacteria fungi ... See more keywords
Peptide Stability Is Important but Not a General Requirement for Antimicrobial and Antibiofilm Activity In Vitro and In Vivo.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00918
Abstract: Peptide stability to proteases has been a major requirement for developing peptide therapeutics. This study investigates the effects of peptide stability on antimicrobial and antibiofilm activity under various conditions. For this purpose, two human cathelicidin-derived… read more here.
Keywords: stability; peptide stability; antimicrobial antibiofilm; antibiofilm activity ... See more keywords
Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00545
Abstract: The development of antimicrobial compounds is now regarded as an urgent problem. Antimicrobial peptides (AMPs) have great potential to become novel antimicrobial drugs. Feleucin-K3 is an α-helical cationic AMP isolated from the skin secretion of… read more here.
Keywords: ala substitution; antimicrobial antibiofilm; key site; substitution ... See more keywords
Promising antimicrobial and antibiofilm activities of reduced graphene oxide-metal oxide (RGO-NiO, RGO-AgO, and RGO-ZnO) nanocomposites
Sign Up to like & getrecommendations! Published in 2021 at "RSC Advances"
DOI: 10.1039/d1ra04542c
Abstract: Microbial infections are considered one of the most dangerous infections for humans due to their resistance to most antimicrobial agents. Nanocomposites-based reduced graphene oxide doped with metal oxides possesses a promising antimicrobial potential. read more here.
Keywords: graphene oxide; rgo; antimicrobial antibiofilm; metal ... See more keywords
In vitro Evaluation of Antimicrobial and Antibiofilm Potentials of Silver Nanoparticles Biosynthesized by Streptomyces griseorubens
Sign Up to like & getrecommendations! Published in 2017 at "Iet Nanobiotechnology"
DOI: 10.1049/iet-nbt.2016.0199
Abstract: This study was performed to determine the antimicrobial and antibiofilm activities of silver nanoparticles (AgNPs) biosynthesised using Streptomyces griseorubens AU2 isolated from soil. The antimicrobial activity of the AgNPs was determined by agar well diffusion,… read more here.
Keywords: silver nanoparticles; streptomyces griseorubens; evaluation antimicrobial; antimicrobial antibiofilm ... See more keywords
Putative application of Najas marina L. extracts as a source of bioactive compounds and their antioxidant, antimicrobial, antibiofilm, and genotoxic properties.
Sign Up to like & getrecommendations! Published in 2023 at "Letters in applied microbiology"
DOI: 10.1093/lambio/ovad055
Abstract: In this research paper, the total phenols (TP), flavonoids (TF), and tannins (TT) content in the acetone and ethyl acetate extracts of Najas marina L. and the identification and quantification of phenolic acids and flavonoids… read more here.
Keywords: antimicrobial antibiofilm; antioxidant antimicrobial; activity; najas marina ... See more keywords
The Current Antimicrobial and Antibiofilm Activities of Synthetic/Herbal/Biomaterials in Dental Application
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/8856025
Abstract: Herbal and chemical products are used for oral care and biofilm treatment and also have been reported to be controversial in the massive trials conducted in this regard. The present review is aimed at evaluating… read more here.
Keywords: antimicrobial antibiofilm; chemical products; current antimicrobial; antibiofilm ... See more keywords
Phytochemical Profiles, Antioxidant and Antimicrobial with Antibiofilm Activities of Wild Growing Potentilla visianii Extracts
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Communications"
DOI: 10.1177/1934578x1801300716
Abstract: We investigated the phytochemical profiles, antioxidant and antimicrobial with antibiofilm activities of methanol and ethyl acetate extracts from the whole plant of Potentilla visianii (Vis. et Panč.) Panč. The major compounds were: epicatechin and quercetin… read more here.
Keywords: phytochemical profiles; profiles antioxidant; potentilla visianii; antimicrobial antibiofilm ... See more keywords
Tackling Microbial Resistance with Isatin-Decorated Thiazole Derivatives: Design, Synthesis, and in vitro Evaluation of Antimicrobial and Antibiofilm Activity
Sign Up to like & getrecommendations! Published in 2022 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s365909
Abstract: Introduction Antibiotic resistance is a global threat that has been increasing recently, especially with antibiotic overuse and misuse. The search for new antibiotics is becoming more and more indispensable. Methods Design and synthesis of isatin… read more here.
Keywords: design synthesis; antimicrobial antibiofilm; decorated thiazole; thiazole derivatives ... See more keywords