Design and synthesis of new 4-methylthiazole derivatives: In vitro and in silico studies of antimicrobial activity
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.130692
Abstract: Abstract The development of resistance against antimicrobial drugs has become a world-wide issue. It is predicted that some or perhaps all the antimicrobial drugs used in clinics will be out of the treatment protocols soon.… read more here.
Keywords: antimicrobial activity; new methylthiazole; antimicrobial drugs; activity ... See more keywords
Microsampling Assays for Pharmacokinetic Analysis and Therapeutic Drug Monitoring of Antimicrobial Drugs in Children: A Critical Review.
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DOI: 10.1097/ftd.0000000000000845
Abstract: PURPOSE With the increasing prevalence of multi-drug resistant organisms, therapeutic drug monitoring (TDM) has become a common tool for assuring the safety and efficacy of antimicrobial drugs at higher doses. Microsampling techniques, including dried blood… read more here.
Keywords: blood; antimicrobial drugs; therapeutic drug; collection ... See more keywords
Therapeutic Drug Monitoring of Antimicrobial Drugs in Neonates: An Opinion Article
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DOI: 10.1097/ftd.0000000000000919
Abstract: Background: Neonatal infections are associated with high morbidity and mortality rates. Optimal treatment of these infections requires knowledge of neonatal pharmacology and integration of neonatal developmental pharmacokinetics (PKs) of antimicrobial drugs in the design of… read more here.
Keywords: antimicrobial drugs; therapeutic drug; article; drugs neonates ... See more keywords
Short history of regulations and approved indications of antimicrobial drugs for food animals in the USA.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12376
Abstract: We review historical availability and regulation, and recent indications of antimicrobial drugs for food animals in the USA. We summarize the timeline of introduction of individual antimicrobial drug classes from the 1930s to present, history… read more here.
Keywords: antimicrobial drugs; animals usa; indications antimicrobial; food animals ... See more keywords
A history of antimicrobial drugs in animals: Evolution and revolution.
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DOI: 10.1111/jvp.12895
Abstract: The evolutionary process of antimicrobial drug (AMD) uses in animals over a mere eight decades (1940-2020) has led to a revolutionary outcome, and both evolution and revolution are ongoing, with reports on a range of… read more here.
Keywords: evolution revolution; pharmacology; antimicrobial drugs; history antimicrobial ... See more keywords
Development of Resistance to Clarithromycin and Amoxicillin-Clavulanic Acid in Lactiplantibacillus plantarum In Vitro Is Followed by Genomic Rearrangements and Evolution of Virulence
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02360-21
Abstract: Ensuring the safety of the use of probiotics is a top priority. We found that increased resistance to popular antimicrobial drugs in Lactiplantibacillus plantarum is accompanied by significant changes in the genomic profile and phenotypic… read more here.
Keywords: antimicrobial drugs; resistance; virulence; lactiplantibacillus plantarum ... See more keywords
Synergistic interaction of eugenol and antimicrobial drugs in eradication of single and mixed biofilms of Candida albicans and Streptococcus mutans
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DOI: 10.1186/s13568-020-01123-2
Abstract: In vitro eradication of the C. albicans and S. mutans mixed biofilms by eugenol alone and in combination with the antimicrobial drugs. Previously characterized strains of C. albicans (CAJ-01 and CAJ-12) and S. mutans MTCC497… read more here.
Keywords: eradication; eugenol; antimicrobial drugs; albicans mutans ... See more keywords
The state of conjunctival flora and its susceptibility to “Vitabakt” in cataract patients compared to other antibiotics used in ophthalmologic practice
Sign Up to like & getrecommendations! Published in 2018 at "Ophthalmology"
DOI: 10.17816/ov11275-79
Abstract: The problem of increasing microbial antibiotic resistance antimicrobial requires a detailed study of all antimicrobial drugs’ spectrum of activity. In the available literature, there are no data on microbial flora in vitro susceptibility to picloxydine.… read more here.
Keywords: antimicrobial drugs; susceptibility; conjunctival flora; state conjunctival ... See more keywords
Assessment of Heavy Metals Contamination and Antimicrobial Drugs Residue in Broiler Edible Tissues in Bangladesh
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DOI: 10.3390/antibiotics12040662
Abstract: There are substantial public health consequences when hazardous heavy metal contaminants and antimicrobial drug residues are present in broiler edible tissues. This study aimed to assess the concentration of antimicrobial drugs and heavy metals residues… read more here.
Keywords: broiler; broiler meat; broiler edible; antimicrobial drugs ... See more keywords
Exposure to Non-Antimicrobial Drugs and Risk of Infection with Antibiotic-Resistant Enterobacteriaceae
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DOI: 10.3390/antibiotics12040789
Abstract: Antimicrobial resistance (AMR) has consistently been linked to antibiotic use. However, the roles of commonly prescribed non-antimicrobial drugs as drivers of AMR may be under-appreciated. Here, we studied a cohort of patients with community-acquired pyelonephritis… read more here.
Keywords: antimicrobial drugs; risk infection; non antimicrobial; exposure non ... See more keywords
Cannabinoids-Promising Antimicrobial Drugs or Intoxicants with Benefits?
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DOI: 10.3390/antibiotics9060297
Abstract: Novel antimicrobial drugs are urgently needed to counteract the increasing occurrence of bacterial resistance. Extracts of Cannabis sativa have been used for the treatment of several diseases since ancient times. However, its phytocannabinoid constituents are… read more here.
Keywords: antimicrobial drugs; cannabinoids promising; drugs intoxicants; promising antimicrobial ... See more keywords