Biophysical characterization of a putative antimicrobial peptide‐binding protein of Escherichia coli highlights its dual functionality
Sign Up to like & getrecommendations! Published in 2025 at "FEBS Letters"
DOI: 10.1002/1873-3468.70068
Abstract: Antimicrobial peptides (AMPs) disrupt the integrity of the bacterial membrane, ultimately leading to their death. In counter‐defense, pathogens are reported to have developed systems such as the sensitivity to antimicrobial peptides (Sap) transport system that… read more here.
Keywords: escherichia coli; system; antimicrobial peptide; characterization putative ... See more keywords
A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202504710
Abstract: Antibody–drug conjugates (ADCs) have transformed cancer therapy but remain limited by their dependence on internalizing antigens, poor applicability to untargetable tumors, and susceptibility to drug resistance. Therefore, a modular antimicrobial‐peptide (AMP)‐based therapeutic system centered on… read more here.
Keywords: serum stable; antimicrobial peptide; peptide based; based delivery ... See more keywords
Improvement of the Antimicrobial Peptide Activity by Means of Chitosan‐Based Nanoparticles
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology Journal"
DOI: 10.1002/biot.70062
Abstract: This study demonstrated the enhancement of the bioactivity of Cm‐p1 and Lip1 antimicrobial peptides (AMPs) against Botrytis cinerea when included within chitosan nanoparticles (CS‐NPs). The physicochemical properties of these AMPs and the adequacy of CS‐NPs… read more here.
Keywords: means chitosan; antimicrobial peptide; improvement antimicrobial; peptide activity ... See more keywords
Cationic amphiphilic peptide: A nature-inspired synthetic antimicrobial peptide.
Sign Up to like & getrecommendations! Published in 2020 at "ChemMedChem"
DOI: 10.1002/cmdc.202000301
Abstract: Antimicrobial peptides are ubiquitous in the multicellular organism and have served as defensive weapons for their successful evolution and throughout their life cycle. These peptides are short cationic amphiphilic polypeptide fewer than 50 amino acids… read more here.
Keywords: peptide; cationic amphiphilic; nature inspired; antimicrobial peptide ... See more keywords
A Polycation Antimicrobial Peptide Mimic without Resistance Buildup against Propionibacterium Acnes.
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201700090
Abstract: A preliminary study is reported for a polycation antimicrobial peptide (AMP) mimic against Propionibacterium acnes, which is associated with acne vulgaris, a common skin condition. Antibiotics are commonly used against P. acnes but buildup of… read more here.
Keywords: buildup; propionibacterium acnes; polycation antimicrobial; antimicrobial peptide ... See more keywords
Hydrogel Complex Containing the Antimicrobial Peptide HX-12C Accelerates Healing of Infected Wounds.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200514
Abstract: Bacterial infections of the wound surface can be painful for patients, and traditional dressings do not effectively address this problem. In this study, we prepared an antimicrobial wound dressing using a novel antimicrobial peptide, HX-12C.… read more here.
Keywords: healing infected; infected wounds; antimicrobial peptide; containing antimicrobial ... See more keywords
Multiple‐Layer Chitosan‐Based Patches Medicated With LTX‐109 Antimicrobial Peptide for Modulated Local Therapy in the Management of Chronic Wounds
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Bioscience"
DOI: 10.1002/mabi.202400375
Abstract: Abstract In response to the critical issue of chronic wound management, this research explores the development of a multiple‐layer biomaterial loaded with LTX‐109 a novel broad‐spectrum topical antimicrobial peptide currently investigated for the treatment of… read more here.
Keywords: layer; antimicrobial peptide; ltx 109; multiple layer ... See more keywords
Self-adhesive Hyaluronic Acid/Antimicrobial Peptide Composite Hydrogel with Antioxidant Capability and Photothermal Activity for Infected Wound Healing.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202200176
Abstract: Bacterial infection can delay wound healing, causing wounds to deteriorate and even threatening the patient's life. Recently, although many composite hydrogels as wound dressing have been developed, it is still highly desired to construct photothermal… read more here.
Keywords: wound healing; infected wound; composite hydrogel; antimicrobial peptide ... See more keywords
Antimicrobial Peptide SAAP‐148‐Functionalized Hydrogels from Photocrosslinkable Polymers with Broad Antibacterial Activity
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Rapid Communications"
DOI: 10.1002/marc.202400785
Abstract: Abstract Antimicrobial peptides (AMPs) are promising alternatives to traditional antibiotics for treating skin wound infections. Nonetheless, their short half‐life in biological environments restricts clinical applicability. Covalent immobilization of AMPs onto suitable substrates offers a comprehensive… read more here.
Keywords: antimicrobial peptide; 148 functionalized; saap 148; peptide saap ... See more keywords
The evolution of the antimicrobial peptide database over 18 years: Milestones and new features
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DOI: 10.1002/pro.4185
Abstract: The antimicrobial peptide database (APD) has served the antimicrobial peptide field for 18 years. Because it is widely used in research and education, this article documents database milestones and key events that have transformed it into… read more here.
Keywords: evolution antimicrobial; database; antimicrobial peptide; database years ... See more keywords
Design, expression, and characterization of the hybrid antimicrobial peptide T‐catesbeianin‐1 based on FyuA
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Peptide Science"
DOI: 10.1002/psc.3059
Abstract: The overuse of antibiotics has resulted in the emergence of antibiotic‐resistant bacteria, which presents an urgent need for new antimicrobial agents. At present, antimicrobial peptides have attracted a great deal of attention from researchers. However,… read more here.
Keywords: peptide; peptide catesbeianin; design expression; hybrid antimicrobial ... See more keywords