Identification of Cancer-Targeted Tropomyosin Inhibitors and Their Synergy with Microtubule Drugs
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DOI: 10.1158/1535-7163.mct-16-0873
Abstract: Actin filaments, with their associated tropomyosin polymers, and microtubules are dynamic cytoskeletal systems regulating numerous cell functions. While antimicrotubule drugs are well-established, antiactin drugs have been more elusive. We previously targeted actin in cancer cells… read more here.
Keywords: antimicrotubule agents; identification cancer; cancer cells; cancer ... See more keywords