A flavone from the ethyl acetate extract of Leea rubra leaves with DNA damage protection and antineoplastic activity
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2022.101244
Abstract: Among the major constituents of Leea rubra (Family Vitaceae) leaves, phenolic and flavonoind compounds are most important for therapeutic purposes and the plant parts have been used in traditional medicine to treat several diseases for… read more here.
Keywords: damage; leea rubra; rubra leaves; flavone ... See more keywords
Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo
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DOI: 10.1038/s41598-018-19410-1
Abstract: The present study was designed to investigate if elevated copper level can be targeted to enhance the efficacy of a significant anticancer drug, imatinib (ITB). The antineoplastic activity of this drug was assessed in the… read more here.
Keywords: drug; copper level; antineoplastic activity; level ... See more keywords
Antineoplastic Activity of Pazopanib in Anaplastic Thyroid Cancer in Primary Culture
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DOI: 10.3390/ijms24032398
Abstract: Anaplastic thyroid cancer (ATC) is a rare and rapidly fatal human cancer. Its usual treatment includes the combination of surgery, external hyperfractionated radiation therapy, and chemotherapy. These treatments permit achieving about 6–10 months of median… read more here.
Keywords: antineoplastic activity; pazopanib; thyroid cancer; anaplastic thyroid ... See more keywords
Antineoplastic Activity of Podophyllotoxin and Juniper Extracts Encapsulated in MPEG-b-PLA Diblock Copolymer Micelles in Cutaneous Squamous Carcinoma Cells
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DOI: 10.3390/ijms26115167
Abstract: Nanotechnology offers alternative approaches to the discovery of anticancer drugs. Hydrophobic bioactive components can be included in the cores of amphiphilic nanocarriers, which leads to the formation of a water-dispersible product with improved bioavailability, facilitated… read more here.
Keywords: diblock copolymer; antineoplastic activity; juniper; mpeg pla ... See more keywords
Disulfiram Enhances the Antineoplastic Activity and Sensitivity of Murine Hepatocellular Carcinoma to 5-FU via Redox Management
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DOI: 10.3390/ph16020169
Abstract: The efficacy of anticancer drug 5-FU is suppressed due to various factors, including severe side effects and decreased insensitivity during prolonged chemotherapy. Elevated endogenous copper (Cu) levels are one of the prominent hallmark features of… read more here.
Keywords: antineoplastic activity; hepatocellular carcinoma; enhances antineoplastic; activity ... See more keywords
Antineoplastic Activity of Rhus trilobata Nutt. (Anacardiaceae) against Ovarian Cancer and Identification of Active Metabolites in This Pathology
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DOI: 10.3390/plants10102074
Abstract: Rhus trilobata (RHTR) is a medicinal plant with cytotoxic activity in different cancer cell lines. However, the active compounds in this plant against ovarian cancer are unknown. In this study, we aimed to evaluate the… read more here.
Keywords: antineoplastic activity; pathology; rhus trilobata; ovarian cancer ... See more keywords