To Take or Not to Take With Meals? Unraveling Issues Related to Food Effects Labeling for Oral Antineoplastic Drugs
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.416
Abstract: There has been controversy regarding whether bioavailability of certain oral oncology drugs should be maximized by taking these medications with food, irrespective of label instructions in the dosing and administration section. To provide insight into… read more here.
Keywords: bioavailability; oral antineoplastic; drug; oncology ... See more keywords
Neurotoxicity of antineoplastic drugs: Mechanisms, susceptibility, and neuroprotective strategies.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in medical sciences"
DOI: 10.1016/j.advms.2020.04.001
Abstract: This review summarizes the adverse effects on the central and/or peripheral nervous systems that may occur in response to antineoplastic drugs. In particular, we describe the neurotoxic side effects of the most commonly used drugs,… read more here.
Keywords: drugs mechanisms; neurotoxicity antineoplastic; nervous system; neurotoxicity ... See more keywords
Computer‐assisted UHPLC–MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.11.014
Abstract: HighlightsA generic UHPLC‐MS method development workflow was proposed for the analysis of antineoplastic drugs.Screening, optimization, virtual refinement and virtual robustness testing were done.Limited handling of toxic compounds was required to perform the whole method development.Complete… read more here.
Keywords: method development; method; uhplc method; optimization ... See more keywords
Role of oxidative stress in cardiotoxicity of antineoplastic drugs.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.06.001
Abstract: Tumors and heart disease are two of the leading causes of human death. With the development of anti-cancer therapy, the survival rate of cancer patients has been significantly improved. But at the same time, the… read more here.
Keywords: cardiotoxicity; role; cancer; antineoplastic drugs ... See more keywords
Assessing variability of antineoplastic drugs handling practices in clinical settings
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Occupational and Environmental Hygiene"
DOI: 10.1080/15459624.2019.1667502
Abstract: Abstract The United States Pharmacopeia (USP) Chapter guidelines will be adopted in the U.S. and Canada in 2019, requiring regular surface sampling for antineoplastic drug (AD) surface contamination as a means of environmental surveillance. USP… read more here.
Keywords: patient administration; staff; variability antineoplastic; variability ... See more keywords
Occupational Exposure in Health Care Personnel to Antineoplastic Drugs and Initiation of Safe Handling in Hong Kong: A Literature Review.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Infusion Nursing"
DOI: 10.1097/nan.0000000000000361
Abstract: Despite the benefits for patients as cancer treatment, antineoplastic drugs may cause adverse effects not only in patients but also in health care personnel. Apart from minor symptoms, antineoplastic agents can cause serious health problems.… read more here.
Keywords: care personnel; antineoplastic drugs; health; health care ... See more keywords
Assessment of verdinexor as a canine P-glycoprotein substrate.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.13123
Abstract: The P-glycoprotein (P-gp) substrate status of antineoplastic drugs intended for veterinary patients is an important characteristic to define for two reasons. First, neoplastic cells expressing P-gp can actively efflux drugs that are P-gp substrates curtailing… read more here.
Keywords: verdinexor; canine; antineoplastic drugs; glycoprotein substrate ... See more keywords
Four-year follow-up of surface contamination by antineoplastic drugs in a compounding unit
Sign Up to like & getrecommendations! Published in 2023 at "Occupational and Environmental Medicine"
DOI: 10.1136/oemed-2022-108623
Abstract: Objectives This study aimed to monitor the contamination by antineoplastic drugs on work surfaces in a compounding unit 4 years after its implementation. Methods This descriptive study was done in a unit performing on average 45 000… read more here.
Keywords: year; contamination; surface; unit ... See more keywords
Use of personal protective equipment while admixing antineoplastic drugs during the COVID-19 pandemic era: Questionnaire survey in Niigata, Japan
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155220932342
Abstract: The Pharmacopeial Convention and the National Institute for Occupational Safety and Health in the US have recommended that health care workers should wear disposable personal protective equipment (PPE) when admixing antineoplastic drugs and should be… read more here.
Keywords: personal protective; number; japan; admixing antineoplastic ... See more keywords
Nursing Assistants' Use of Personal Protective Equipment Regarding Contact With Excreta Contaminated With Antineoplastic Drugs.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology nursing forum"
DOI: 10.1188/19.onf.689-700
Abstract: PURPOSE To examine the feasibility of observing and interviewing nursing assistants about handling of antineoplastic drugs contaminated with excreta, acceptability of a measure of personal protective equipment (PPE) use with nursing assistants, and predictors of… read more here.
Keywords: antineoplastic drugs; nursing assistants; personal protective; nursing ... See more keywords
Knowledge about antineoplastic drugs: implications for the health of nursing workers in a general hospital.
Sign Up to like & getrecommendations! Published in 2021 at "Revista brasileira de enfermagem"
DOI: 10.1590/0034-7167-2021-0025
Abstract: OBJECTIVES to understand, from a worker's health perspective, the knowledge of nursing professionals about the use of antineoplastic drugs in a general hospital. METHODS a descriptive and exploratory study with a qualitative approach. It was… read more here.
Keywords: knowledge antineoplastic; hospital; nursing; health ... See more keywords