NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia
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DOI: 10.1007/s10637-020-01028-8
Abstract: Chronic myeloid leukemia (CML) is successfully treated with BCR-ABL1 tyrosine kinase inhibitors, but a significant percentage of patients develop resistance. Insulin receptor substrate 1 (IRS1) has been shown to constitutively associate with BCR-ABL1, and IRS1-specific… read more here.
Keywords: igf1r irs1; irs1; bcr abl1; antineoplastic effects ... See more keywords
Antineoplastic Effects of Ankaferd Hemostat
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DOI: 10.1155/2022/2665903
Abstract: Materials and Methods Up to June 2022, literature searches were performed using the internet search engines Medline, Google Scholar, and Embase: Ankaferd. PRISMA flow diagram described the Ankaferd search. Results ABS have important effects in… read more here.
Keywords: ankaferd hemostat; antineoplastic effects; cancer; role ... See more keywords
Near-infrared fluorescence imaging and photodynamic therapy with indocyanine green lactosome has antineoplastic effects for hepatocellular carcinoma
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DOI: 10.1371/journal.pone.0183527
Abstract: Background Anticancer agents and operating procedures have been developed for hepatocellular carcinoma (HCC) patients, but their prognosis remains poor. It is necessary to develop novel diagnostic and therapeutic strategies for HCC to improve its prognosis.… read more here.
Keywords: hepatocellular carcinoma; icg lactosome; antineoplastic effects; fluorescence ... See more keywords
Investigation of the Antineoplastic Effects of 2-(4-Chlorophenyl)-13α-Estrone Sulfamate against the HPV16-Positive Human Invasive Cervical Carcinoma Cell Line SiHa
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DOI: 10.3390/ijms24076625
Abstract: Cervical carcinoma is one of the most frequent malignant gynecological cancers in women of reproductive age. Because of the poor tolerability of currently available chemotherapeutic agents, efforts have been focused on developing innovative molecules, including… read more here.
Keywords: cervical carcinoma; cell line; antineoplastic effects; estrone sulfamate ... See more keywords