Articles with "antineoplastic vinblastine" as a keyword



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Ethyl Methane Sulfonate and Sodium Azide-Mediated Chemical and X-ray-Mediated Physical Mutagenesis Positively Regulate Peroxidase 1 Gene Activity and Biosynthesis of Antineoplastic Vinblastine in Catharanthus roseus

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Published in 2022 at "Plants"

DOI: 10.3390/plants11212885

Abstract: Catharanthus roseus synthesizes bioactive therapeutic metabolites, known as monoterpenoid indole alkaloids (MIAs), including antineoplastic vinblastine and vincristine, which have high global demand, and antihypertensive ajmalicine, a serpentine. However, the in planta biosynthesis and accumulation of… read more here.

Keywords: biosynthesis; sodium azide; mutagenesis; roseus ... See more keywords