TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal
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DOI: 10.1111/jcmm.14099
Abstract: Safranal, contained in Crocus sativus L., exerts anti‐inflammatory and analgesic effects. However, the underlying mechanisms for such effects are poorly understood. We explored whether safranal targets the transient receptor potential ankyrin 1 (TRPA1) channel, which… read more here.
Keywords: trpa1; antinociceptive properties; trpa1 mediates; crocus sativus ... See more keywords
Further Antinociceptive Properties of Naringenin on Acute and Chronic Pain in Mice
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DOI: 10.1177/1934578x1701200915
Abstract: Naringenin (NG) is a flavanone abundant in grapefruit and other citrus fruits that presents several pharmacological effects, such as antioxidant, anti-inflammatory, analgesic, among others. We investigated the antinociception of systemic administration of naringenin (NG) and… read more here.
Keywords: naringenin acute; antinociceptive properties; pain; chronic pain ... See more keywords