Nrf2 Signaling in Heart Failure: Expression of Nrf2, Keap1, Antioxidant and Detoxification Genes in Dilated or Ischemic Cardiomyopathy.
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DOI: 10.1152/physiolgenomics.00079.2021
Abstract: Increased levels of oxidative stress have been found with heart failure. Whether failing hearts express antioxidant and detoxification enzymes have not been addressed systematically. Nrf2 gene encodes a transcription factor that regulates the expression of… read more here.
Keywords: detoxification; heart failure; antioxidant detoxification; expression ... See more keywords