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Published in 2020 at "Biocatalysis and agricultural biotechnology"
DOI: 10.1016/j.bcab.2020.101556
Abstract: Abstract Parasitic diseases are considered a serious problem due to the lack of appropriate vaccines for the prevention and treatment of these diseases and the appearance of drug-resistant parasites. This study tries to evaluate the…
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Keywords:
crassipes leaves;
activity eichhornia;
extract antiparasitic;
eichhornia crassipes ... See more keywords
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Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103116
Abstract: Novel N-substituted noscapine derivatives were synthesized by a three-component Strecker reaction of cyclic ether of N-nornoscapine with varied aldehydes, in the presence of cyanide ion. Moreover, the corresponding amides were synthesized by the oxidation of…
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Keywords:
molecular docking;
antiparasitic activity;
activity;
substituted noscapine ... See more keywords
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Published in 2017 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2017.05.003
Abstract: Avena sativa L., 1753 (Poaceae) is used as feed for livestock and as a crop rotation agent. The purpose of the study was to examine the molecular mechanisms behind the antihelminth activity of the oat…
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Keywords:
avenacosides intestinal;
intestinal nematodes;
larvae;
activity avenacosides ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-90719-0
Abstract: Chagas disease is caused by Trypanosoma cruzi and affects thousands of people. Drugs currently used in therapy are toxic and have therapeutic limitations. In addition, the genetic diversity of T. cruzi represents an important variable…
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Keywords:
different strains;
sodium diethyldithiocarbamate;
detc;
antiparasitic activity ... See more keywords
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1
Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/4999797
Abstract: Eurycoma longifolia or Tongkat Ali (family: Simaroubaceae) has the potential to be utilised as an antimicrobial and antiparasitic agent that correlated with its traditional use to treat jaundice, malaria, antiseptic agent, and many more. This…
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Keywords:
antimicrobial antiparasitic;
antiparasitic activity;
review;
eurycoma longifolia ... See more keywords
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Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220507011719
Abstract: BACKGROUND In a scenario of increased pathogens with multidrug resistance phenotypes, it is necessary to seek new pharmacological options. This fact is responsible for an increase in neoplasms and multiresistant parasitic diseases. In turn, snake…
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Keywords:
antiparasitic activity;
antitumor antiparasitic;
activity antimicrobial;
antimicrobial peptides ... See more keywords
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2
Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11010219
Abstract: A series of fourteen pyrimido[1,2-a]benzimidazole compounds was prepared by straightforward heterocyclic chemistry and oxidation methods. The new pyrimidobenzimidazole derivative 2a with a 3-fluorophenyl substituent was identified as a new antiparasitic compound showing excellent activities against…
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Keywords:
antiparasitic activity;
chemistry;
fluorophenyl;
activity fluorophenyl ... See more keywords
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1
Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072246
Abstract: Nitrogen-containing atoms in their core structures have been exclusive building blocks in drug discovery and development. One of the most significant and well-known heterocycles is the 1,3,4-thidiazole nucleus, which is found in a wide range…
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Keywords:
antiparasitic activity;
exploring antiparasitic;
activity tris;
gondii ... See more keywords
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1
Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11121424
Abstract: Metals have been used in medicine since ancient times for the treatment of different ailments with various elements such as iron, gold and arsenic. Metal complexes have also been reported to show antibiotic and antiparasitic…
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Keywords:
antiparasitic activity;
organotin derivatives;
activity;
leishmania donovani ... See more keywords
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Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051535
Abstract: Chagas disease (CD) caused by the protozoan Trypanosoma cruzi affects more than six million people worldwide. Treatment is restricted to benznidazole (Bz) and nifurtimox (Nf) that display low activity in the later chronic stage besides…
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Keywords:
naphthoquinone plumbagin;
antiparasitic activity;
trypanosoma cruzi;
extracts naphthoquinone ... See more keywords