Evaluation of the antiparasitic and antifungal activities of new synthetic piperlongumine-type cinnamide derivatives: booster effect by halogen substituents.
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DOI: 10.1002/cmdc.202300132
Abstract: A series of synthetic N-acylpyrrolidone and -piperidone derivatives of the natural alkaloid piperlongumine were prepared and tested for their activities against Leishmania major and Toxoplasma gondii parasites. Replacement of one of the aryl meta-methoxy groups… read more here.
Keywords: piperlongumine; antifungal activities; activities new; antiparasitic antifungal ... See more keywords