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   Articles with "antiphage defense" as a keyword



An enterococcal phage protein inhibits type IV restriction enzymes involved in antiphage defense

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recommendations! Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-51346-1

Abstract: The prevalence of multidrug resistant (MDR) bacterial infections continues to rise as the development of antibiotics needed to combat these infections remains stagnant. MDR enterococci are a major contributor to this crisis. A potential therapeutic… read more here.

Keywords: phage; antiphage defense; restriction; type restriction ... See more keywords

Pseudomonas aeruginosa as a model bacterium in antiphage defense research

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recommendations! Published in 2025 at "FEMS Microbiology Reviews"

DOI: 10.1093/femsre/fuaf014

Abstract: Abstract Bacteriophages, or phages, depend on their bacterial hosts for proliferation, leading to a coevolutionary relationship characterized by on-going arms races, where bacteria evolve diverse antiphage defense systems. The development of in silico methods and… read more here.

Keywords: defense research; defense systems; antiphage defense; antiphage ... See more keywords

Systematic discovery of antiphage defense systems in the microbial pangenome

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recommendations! Published in 2018 at "Science"

DOI: 10.1126/science.aar4120

Abstract: Maps of defense arsenals in microbial genomes To survive the attack of foreign invaders such as viruses and plasmids, bacteria and archaea fight back with immune systems that are usually clustered in “defense islands” in… read more here.

Keywords: antiphage defense; defense; discovery; defense islands ... See more keywords

Bacterial reverse transcriptase synthesizes long poly-A-rich cDNA for antiphage defense.

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recommendations! Published in 2025 at "Science"

DOI: 10.1126/science.ads4639

Abstract: Prokaryotic defense-associated reverse transcriptases (DRTs) were recently identified with antiviral functions; however, their functional mechanisms remain largely unexplored. Here we show that DRT9 forms a hexameric complex with its upstream non-coding RNA (ncRNA) to mediate… read more here.

Keywords: antiphage defense; long poly; bacterial reverse; defense ... See more keywords