Antiproliferative and cytotoxic secondary metabolites from fruits of Leplaea mayombensis
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DOI: 10.1080/14786419.2017.1402321
Abstract: Abstract Two new seco-lanostane-type triterpenes, named mayomlactones A (1) and B (2) were isolated from the fruits of Leplaea mayombensis together with 10 known compounds (3–12). Structures of the new compounds were elucidated by extensive… read more here.
Keywords: cytotoxic secondary; antiproliferative cytotoxic; compounds showed; leplaea mayombensis ... See more keywords
New Affordable Methods for Large-Scale Isolation of Major Olive Secoiridoids and Systematic Comparative Study of Their Antiproliferative/Cytotoxic Effect on Multiple Cancer Cell Lines of Different Cancer Origins
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DOI: 10.3390/ijms24010003
Abstract: Olive oil phenols (OOPs) are associated with the prevention of many human cancers. Some of these have been shown to inhibit cell proliferation and induce apoptosis. However, no systematic comparative study exists for all the… read more here.
Keywords: cell lines; antiproliferative cytotoxic; cancer; cancer cell ... See more keywords
Antiproliferative and Cytotoxic Cytochalasins from Sparticola triseptata Inhibit Actin Polymerization and Aggregation
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DOI: 10.3390/jof8060560
Abstract: Laying the groundwork on preliminary structure–activity relationship study relating to the disruptive activity of cytochalasan derivatives on mammalian cell actin cytoskeleton, we furthered our study on the cytochalasans of the Dothideomycetes fungus, Sparticola triseptata. A… read more here.
Keywords: antiproliferative cytotoxic; sparticola triseptata; triseptata inhibit; cytotoxic cytochalasins ... See more keywords