Assessment of selected medicinal plants indigenous to West Africa for antiprotozoal activity
Sign Up to like & getrecommendations! Published in 2017 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2017.08.002
Abstract: Abstract Ethnopharmacological relevance The disease burden of protozoal infections is enormous in West Africa and other developing regions of the world. Malaria is one of the most important parasitic disease in tropical areas caused by… read more here.
Keywords: west africa; brucei; medicinal plants; chloroform ... See more keywords
Synthesis of chalcone derivatives by Claisen-Schmidt condensation and in vitro analyses of their antiprotozoal activities.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2140337
Abstract: Chalcone is a molecule with known biological activities. Based on this, a series of chalcone derivatives bearing methyl, phenyl or furanyl substituents at different positions of A and B rings were synthesised, characterised, and evaluated… read more here.
Keywords: chalcone derivatives; claisen schmidt; schmidt condensation; chalcone ... See more keywords
Recent Advances in the Discovery of Novel Antiprotozoal Agents
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DOI: 10.3390/molecules24213886
Abstract: Parasitic diseases have serious health, social, and economic impacts, especially in the tropical regions of the world. Diseases caused by protozoan parasites are responsible for considerable mortality and morbidity, affecting more than 500 million people… read more here.
Keywords: antiprotozoal agents; advances discovery; discovery novel; recent advances ... See more keywords
Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction
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DOI: 10.3390/molecules26206181
Abstract: Various nor-triterpene alkaloids of Buxus (B.) sempervirens L. have shown remarkable in vitro activity against the causative agents of tropical malaria and East African sleeping sickness. To identify further antiprotozoal compounds of this plant, 20… read more here.
Keywords: antiprotozoal compounds; buxus sempervirens; compounds buxus; sempervirens pls ... See more keywords
Flavonoids from Piper Species as Promising Antiprotozoal Agents against Giardia intestinalis: Structure-Activity Relationship and Drug-Likeness Studies
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DOI: 10.3390/ph15111386
Abstract: Diarrhea diseases caused by the intestinal protozoan parasite Giardia intestinalis are a major global health burden. Moreover, there is an ongoing need for novel anti-Giardia drugs due to drawbacks with currently available treatments. This paper… read more here.
Keywords: structure activity; piper species; activity; giardia intestinalis ... See more keywords