Involvement of spinal cannabinoid receptors in the antipruritic effects of WIN 55,212‐2, a cannabinoid receptor agonist
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DOI: 10.1111/ced.13398
Abstract: Cannabinoids have been used for their analgesic and euphoric effects for millennia, but recently the antipruritic effects of cannabis have been discovered. Considering the similarities between pain and itch sensations, we hypothesized that cannabinoid receptors… read more here.
Keywords: effects win; receptors antipruritic; cannabinoid receptors; spinal cannabinoid ... See more keywords
Druggable Targets and Compounds with Both Antinociceptive and Antipruritic Effects
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DOI: 10.3390/ph15070892
Abstract: Pain and itch are both important manifestations of various disorders, such as herpes zoster, atopic dermatitis, and psoriasis. Growing evidence suggests that both sensations have shared mediators, overlapping neural circuitry, and similarities in sensitization processes.… read more here.
Keywords: antinociceptive antipruritic; antipruritic effects; pain itch; druggable targets ... See more keywords