Assessment of electroencephalography modification by antipsychotic drugs in patients with schizophrenia spectrum disorders using frontier orbital theory: A preliminary study.
Sign Up to like & getrecommendations! Published in 2023 at "Neuropsychopharmacology reports"
DOI: 10.1002/npr2.12318
Abstract: AIM Schizophrenia is characterized by an abnormality in electroencephalography (EEG), which can be affected by antipsychotic drugs. Recently, the mechanism underlying these EEG alterations in schizophrenia patients was reframed from the perspective of redox abnormalities.… read more here.
Keywords: schizophrenia spectrum; antipsychotic drugs; homo lumo; energy ... See more keywords
Long‐term efficacy of antipsychotic drugs in initially acutely ill adults with schizophrenia: systematic review and network meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "World Psychiatry"
DOI: 10.1002/wps.21089
Abstract: Most acute phase antipsychotic drug trials in schizophrenia last only a few weeks, but patients must usually take these drugs much longer. We examined the long‐term efficacy of antipsychotic drugs in acutely ill patients using… read more here.
Keywords: antipsychotic drugs; meta analysis; network meta; efficacy ... See more keywords
Severe parkinsonism under treatment with antipsychotic drugs
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-019-01060-7
Abstract: The aim of the study was to assess rates of severe parkinsonism related to different antipsychotic drugs (APDs) using data from an observational pharmacovigilance programme in German-speaking countries—Arzneimittelsicherheit in der Psychiatrie (AMSP). Data on APD… read more here.
Keywords: potency; generation; parkinsonism; rates severe ... See more keywords
Effect fingerprints of antipsychotic drugs on neural networks in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-019-02050-8
Abstract: We compared the acute effect of typical (haloperidol) and atypical (aripiprazole, clozapine, olanzapine) antipsychotic drugs (APDs) on spontaneous electrophysiological activity of in vitro neuronal networks cultured on microelectrode arrays (MEAs). Network burst analysis revealed a… read more here.
Keywords: apds; network; effect; effect fingerprints ... See more keywords
QSAR modeling, molecular docking and ADMET/pharmacokinetic studies: a chemometrics approach to search for novel inhibitors of norepinephrine transporter as potent antipsychotic drugs
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-020-01902-5
Abstract: Chemometrics study that relates biological activity to physicochemical descriptors of a molecule and the prediction of absorption, distribution, metabolism, excretion and toxicity (ADMET) properties in advance are important steps in drugs discovery. In this study,… read more here.
Keywords: norepinephrine transporter; chemometrics approach; admet pharmacokinetic; inhibitors norepinephrine ... See more keywords
Evolution of MRI characteristics of heatstroke in a patient with schizophrenia maintained with antipsychotic drugs
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-018-0990-0
Abstract: Although heatstroke commonly occurs in summer, herein, we present a case of heatstroke that occurred in March. The patient has been schizophrenic for over 20 years and has been receiving long-term medications, such as lithium carbonate,… read more here.
Keywords: evolution; mri characteristics; characteristics heatstroke; evolution mri ... See more keywords
[Hip fractures in patients treated with antipsychotic drugs. Study of retrospective cohorts in Catalonia].
Sign Up to like & getrecommendations! Published in 2021 at "Atencion primaria"
DOI: 10.1016/j.aprim.2021.102171
Abstract: OBJECTIVE To evaluate the incidence of hip fracture in patients with antipsychotic treatment, comparing it with that of individuals who have not been treated with antipsychotics. DESIGN Retrospective cohort study of patients treated with antipsychotic… read more here.
Keywords: patients treated; hip; non tap; treated antipsychotic ... See more keywords
Repurposing psychiatric drugs as anti-cancer agents.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.01.058
Abstract: Cancer is a major public health problem and one of the leading contributors to the global disease burden. The high cost of development of new drugs and the increasingly severe burden of cancer globally have… read more here.
Keywords: psychiatric drugs; drugs anti; repurposing psychiatric; cancer ... See more keywords
Use of antipsychotic drugs in dermatology.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics in dermatology"
DOI: 10.1016/j.clindermatol.2018.08.006
Abstract: Antipsychotic drugs can be beneficial in dermatology because of their both central nervous system and peripheral effects. All antipsychotic drugs have a central postsynaptic dopamine D2 receptor blocking effect, which underlies their antipsychotic action. The… read more here.
Keywords: dermatology; receptor blocking; effect; dermatology use ... See more keywords
Antipsychotic drugs for elderly patients with schizophrenia: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2018.09.007
Abstract: Elderly patients with schizophrenia are a particularly vulnerable group often excluded from clinical trials. Currently there is no evidence-synthesis about the efficacy and safety of antipsychotics in this subgroup. We reviewed all randomized-controlled-trials, about antipsychotics… read more here.
Keywords: drugs elderly; patients schizophrenia; elderly patients; meta ... See more keywords
Tardive dyskinesia: Epidemiology
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2018.02.007
Abstract: The term tardive syndrome (TS) encompasses a few different phenomenologic conditions, some of which occur in isolation and others in association with each other. This, along with the unusual confound for a drug side effect,… read more here.
Keywords: antipsychotic drugs; drug; generation; epidemiology ... See more keywords