Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-018-0323-6
Abstract: Antipsychotic-induced weight gain (AIWG) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. We aimed to review the progress of pharmacogenetic studies… read more here.
Keywords: antipsychotic induced; induced weight; aiwg chinese; chinese population ... See more keywords
Antipsychotic-induced Hyperprolactinemia in aging populations: Prevalence, implications, prevention and management
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.109941
Abstract: This paper reviews the prevalence, implications, prevention and management of antipsychotic-induced hyperprolactinemia in aging populations. Antipsychotics are indicated mainly for the treatment of psychotic illness but are also used in other conditions. Complications induced by… read more here.
Keywords: antipsychotic induced; hyperprolactinemia; management; prevalence implications ... See more keywords
T4 and waist:hip ratio as biomarkers of antipsychotic-induced weight gain in Han Chinese inpatients with schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2017.11.010
Abstract: Second-generation antipsychotic agents (SGAs) cause serious metabolic side effects, including weight gain, dyslipidemia, and glucose metabolism abnormalities, which occur by unknown mechanisms. Therefore, the search for prospective markers for antipsychotic-induced weight gain (AIWG) has been… read more here.
Keywords: antipsychotic induced; induced weight; gain; han chinese ... See more keywords
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects
Sign Up to like & getrecommendations! Published in 2017 at "Nature Neuroscience"
DOI: 10.1038/nn.4616
Abstract: Antipsychotic drugs remain the standard for schizophrenia treatment. Despite their effectiveness in treating hallucinations and delusions, prolonged exposure to antipsychotic medications leads to cognitive deficits in both schizophrenia patients and animal models. The molecular mechanisms… read more here.
Keywords: transcription; antipsychotic induced; effects antipsychotic; transcription via ... See more keywords
Adjunctive metformin for antipsychotic-induced dyslipidemia: a meta-analysis of randomized, double-blind, placebo-controlled trials
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-0785-y
Abstract: Antipsychotic-induced dyslipidemia could increase the risk of cardiovascular diseases. This is a meta-analysis of randomized double-blind placebo-controlled trials to examine the efficacy and safety of adjunctive metformin for dyslipidemia induced by antipsychotics in schizophrenia. The… read more here.
Keywords: antipsychotic induced; adjunctive metformin; analysis; placebo ... See more keywords
Antipsychotic-induced Tardive dyskinesia: from biological basis to clinical management
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2017.1361322
Abstract: ABSTRACT Introduction: Tardive dyskinesia (TD) is a chronic and disabling movement disorder with a complex pathophysiological basis. A significant percentage of patients does not receive correct diagnosis, resulting in delayed or inaccurate treatment and poor… read more here.
Keywords: antipsychotic induced; basis; induced tardive; dyskinesia biological ... See more keywords
Does the gut microbiome mediate antipsychotic-induced metabolic side effects in schizophrenia?
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Safety"
DOI: 10.1080/14740338.2022.2042251
Abstract: ABSTRACT Introduction Second-generation antipsychotics (SGAs) are the most effective treatment for people with schizophrenia. Despite their effectiveness in treating psychotic symptoms, they have been linked to metabolic, cardiovascular and gastrointestinal side-effects. The gut microbiome has… read more here.
Keywords: antipsychotic induced; side; side effects; induced side ... See more keywords
There has been very little progress in treating or preventing antipsychotic-induced tardive dyskinesia
Sign Up to like & getrecommendations! Published in 2018 at "Evidence-Based Mental Health"
DOI: 10.1136/ebmental-2018-300006
Abstract: Methods of the study This systematic review1 evaluated any intervention for treating or preventing deterioration of symptoms of antipsychotic-induced TD in adult patients. Included were all relevant studies, regardless of language, about adults who had… read more here.
Keywords: treating preventing; antipsychotic induced; preventing antipsychotic; progress treating ... See more keywords
Metformin for antipsychotic-induced weight gain: Statistical curiosities
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881117693736
Abstract: 1. In Table 2, the mean between-groups difference for body-mass index (BMI) falls outside the 95% confidence interval (CI); this is statistically impossible. 2. In the same table, the 95% CI for the between-groups difference… read more here.
Keywords: antipsychotic induced; induced weight; bmi; weight gain ... See more keywords
Antipsychotic-induced weight gain: exploring the role of psychiatrists in managing patients' physical health - challenges, current options and direction for future care.
Sign Up to like & getrecommendations! Published in 2023 at "BJPsych bulletin"
DOI: 10.1192/bjb.2023.29
Abstract: Antipsychotics and severe mental illness (SMI) are associated with weight gain, and obesity increases the risks of cardiometabolic disease and premature death. These present management and liability issues for psychiatrists. Physical healthcare for people with… read more here.
Keywords: health; antipsychotic induced; gain; induced weight ... See more keywords
Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2017 at "Current Neuropharmacology"
DOI: 10.2174/1570159x14666160606093602
Abstract: Chronic prescription of antipsychotics seems to lose its therapeutic benefits in the prevention of recurring psychotic symptoms. In many instances, the occurrence of relapse from initial remission is followed by an increase in dose of… read more here.
Keywords: supersensitivity psychosis; antipsychotic induced; dopamine supersensitivity; dopamine ... See more keywords