Grey matter connectome abnormalities and age-related effects in antipsychotic-naive schizophrenia
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103749
Abstract: Background Convergent evidence is increasing to indicate progressive brain abnormalities in schizophrenia. Knowing the brain network features over the illness course in schizophrenia, independent of effects of antipsychotic medications, would extend our sight on this… read more here.
Keywords: age; antipsychotic naive; age related; schizophrenia ... See more keywords
M96 GENOME-WIDE DNA METHYLATION ANALYSIS IN A LONGITUDINAL COHORT OF ANTIPSYCHOTIC-NAIVE FIRST EPISODE OF PSYCHOSIS PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.403
Abstract: Background The study of the early stages of schizophrenia, the First-Episode Psychosis (FEP), is critical given that brain abnormalities and cognitive deficits are already present. Although less investigated than chronic schizophrenia, FEP individuals have a… read more here.
Keywords: first episode; cohort; antipsychotic naive; dna methylation ... See more keywords
164. Association Between Glutamate + Glutamine in the Left Temporoparietal Junction and Mismatch Negativity (MMN) in Antipsychotic-Naive/Free Schizophrenia Patients With Auditory Hallucinations.
Sign Up to like & getrecommendations! Published in 2017 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx021.222
Abstract: Abstract Background: Mismatch negativity (MMN), a biomarker for schizophrenia, is understood to be dependent on glutamatergic neurotransmission. Although both glutamate and MMN are considered to be of high relevance to schizophrenia pathophysiology, only one study… read more here.
Keywords: naive free; schizophrenia; auditory hallucinations; antipsychotic naive ... See more keywords
Altered White Matter Connectivity Within and Between Networks in Antipsychotic-Naive First-Episode Schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx048
Abstract: Analyzing the schizophrenia connectome can identify illness-related alterations in connectivity across the brain. An important question that remains unanswered is whether connectivity alterations are already evident at the onset of illness, before treatment with antipsychotic… read more here.
Keywords: schizophrenia; connectivity; naive first; antipsychotic naive ... See more keywords