Articles with "antipsychotics effect" as a keyword



Multitarget Derivatives of D2AAK1 as Potential Antipsychotics: The Effect of Substitution in the Indole Moiety

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Published in 2022 at "ChemMedChem"

DOI: 10.1002/cmdc.202200238

Abstract: Schizophrenia is a complex disease which is best treated with multitarget drugs, such as atypical antipsychotics. Previously, using structure‐based virtual screening, we found a virtual hit, D2AAK1, with nanomolar affinity for dopamine and serotonin receptors… read more here.

Keywords: multitarget; antipsychotics effect; derivatives d2aak1; d2aak1 potential ... See more keywords