Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.0674
Abstract: Importance Prenatal antiseizure medication (ASM) exposure has been associated with adverse early neurodevelopment, but associations with a wider range of psychiatric end points have not been studied. Objective To examine the association between prenatal exposure… read more here.
Keywords: psychiatric disorders; antiseizure medication; childhood adolescence; prenatal exposure ... See more keywords
Comparative Safety of Antiseizure Medication Monotherapy for Major Malformations
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26561
Abstract: This study was undertaken to examine the comparative safety of antiseizure medication (ASM) monotherapy in pregnancy with respect to risk of major congenital malformations (MCMs), overall and by MCM subtype. read more here.
Keywords: antiseizure medication; safety antiseizure; comparative safety;
Antiseizure medication discovery: Recent and future paradigm shifts.
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia open"
DOI: 10.1002/epi4.12581
Abstract: Despite the ever-increasing number of available options for the treatment of epilepsies and the remarkable advances on the understanding of their pathophysiology, the proportion of refractory patients has remained approximately unmodified during the last 100… read more here.
Keywords: antiseizure; discovery recent; antiseizure medication; future paradigm ... See more keywords
Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy: A multicenter retrospective chart review
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12695
Abstract: Guidelines suggest considering antiseizure medication (ASM) discontinuation in patients with epilepsy who become seizure‐free. Little is known about how discontinuation decisions are being made in practice. We measured the frequency of, and factors associated with,… read more here.
Keywords: patients epilepsy; antiseizure medication; discussions decisions; frequency factors ... See more keywords
Antiseizure medication withdrawal risk estimation and recommendations: A survey of American Academy of Neurology and EpiCARE members
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12696
Abstract: Choosing candidates for antiseizure medication (ASM) withdrawal in well‐controlled epilepsy is challenging. We evaluated (a) the correlation between neurologists' seizure risk estimation (“clinician predictions”) vs calculated predictions, (b) how viewing calculated predictions influenced recommendations, and… read more here.
Keywords: neurology; antiseizure medication; withdrawal; risk estimation ... See more keywords
Correlation of drug dose estimated from national prescription registers with mean blood level of antiseizure medication in pregnancy
Sign Up to like & getrecommendations! Published in 2024 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5811
Abstract: The purpose was to examine the correlation of antiseizure medication drug dose estimated from prescription fill records from prescription registers with blood levels during pregnancy. read more here.
Keywords: prescription registers; antiseizure medication; drug dose; drug ... See more keywords
Brain function and network features in patients with chronic epilepsy before and after antiseizure medication withdrawal
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2021.106740
Abstract: OBJECTIVES A considerable proportion of epilepsy patients who achieved long-term seizure freedom with standardized treatment of antiseizure medication will attempt to withdraw medications. Epilepsy is currently considered as a network disease, however, the characteristics of… read more here.
Keywords: network; medication withdrawal; antiseizure medication; medication ... See more keywords
Trends in use of antiseizure medication and treatment pattern during the first trimester in the German Embryotox cohort
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-83060-9
Abstract: Because of their developmental toxicity, some antiseizure medication (ASM) should be avoided during pregnancy. This may lead to discontinuation or switching of ASM after recognition of pregnancy, but some of these changes may be suboptimal.… read more here.
Keywords: non recommended; treatment pattern; treatment; antiseizure medication ... See more keywords
KCNQ2 -Related Epilepsy: Genotype–Phenotype Relationship with Tailored Antiseizure Medication (ASM)—A Systematic Review
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DOI: 10.1055/a-2060-4576
Abstract: Abstract Autosomal dominant mutations of the KCNQ2 gene can cause two epileptic disorders: benign familial neonatal seizures (BFNS) and developmental epileptic encephalopathy (DEE). This systematic review aims to identify the best reported therapy for these… read more here.
Keywords: phenotype; antiseizure medication; genotype; systematic review ... See more keywords
Antiseizure medication-induced obsessive-compulsive disorder and tic disorder: a pragmatic review
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2022.2117614
Abstract: ABSTRACT Introduction With a lifetime prevalence of 2.3%, obsessive compulsive disorder is a chronic, disabling condition that is associated with significant social and occupational impairment. Up to 30% of individuals with obsessive-compulsive disorder have a… read more here.
Keywords: antiseizure medication; compulsive disorder; disorder; induced obsessive ... See more keywords
Antiseizure medication treatment pathways for US Medicare beneficiaries with newly treated epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17226
Abstract: This study was undertaken to characterize antiseizure medication (ASM) treatment pathways in Medicare beneficiaries with newly treated epilepsy. read more here.
Keywords: pathways medicare; antiseizure medication; treatment pathways; newly treated ... See more keywords