Tolerability of Antiseizure Medications in Individuals With Newly Diagnosed Epilepsy.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2020.0032
Abstract: Importance Tolerability is a key determinant of the effectiveness of epilepsy treatment. It is important to evaluate whether the overall tolerability has improved. Objective To identify factors associated with poor tolerability of antiseizure medications (ASMs)… read more here.
Keywords: epilepsy; newly diagnosed; tolerability antiseizure; tolerability ... See more keywords
Presurgical cognitive status in patients with low‐grade glioma and epilepsy: Testing the effects of seizures, antiseizure medications, and tumor localization
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2560
Abstract: Low‐grade gliomas (LGGs) are frequently associated with epilepsy. There are few studies addressing the impact of seizures, antiseizure medications (ASMs), and lesion localization on presurgery cognitive functioning. read more here.
Keywords: antiseizure medications; localization; presurgical cognitive; seizures antiseizure ... See more keywords
Combination of antiseizure medications phenobarbital, ketamine and midazolam reduces soman-induced epileptogenesis and brain pathology in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Epilepsia open"
DOI: 10.1002/epi4.12552
Abstract: OBJECTIVE Cholinergic-induced status epilepticus (SE) is associated with a loss of synaptic gamma-aminobutyric acid A receptors (GABAA R) and an increase in N-methyl-D-aspartate receptors (NMDAR) and amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR) that may contribute to pharmacoresistance… read more here.
Keywords: ketamine; midazolam; pathology; soman induced ... See more keywords
Medical treatment in infants and young children with epilepsy: Off‐label use of antiseizure medications. Survey Report of ILAE Task Force Medical Therapies in Children
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12666
Abstract: Antiseizure medications (ASMs) remain the mainstay of epilepsy treatment. These ASMs have mainly been tested in trials in adults with epilepsy, which subsequently led to market authorization (MA). For treatment of – especially young –… read more here.
Keywords: antiseizure medications; young children; children epilepsy; label use ... See more keywords
Safety and efficacy of rapid withdrawal of antiseizure medications during long‐term video‐electroencephalogram monitoring in children with drug‐resistant epilepsy: A retrospective study
Sign Up to like & getrecommendations! Published in 2023 at "Epilepsia Open"
DOI: 10.1002/epi4.12680
Abstract: Performing long‐term video‐electroencephalographic monitoring (LTVEM) to obtain the ictal electroencephalogram (EEG) is important for presurgical evaluation. This study aimed at investigating the safety and efficacy of our protocol developed at Peking University First Hospital (PUFH)… read more here.
Keywords: antiseizure medications; long term; withdrawal antiseizure; safety efficacy ... See more keywords
Changes in the use of antiseizure medications in children and adolescents in Norway, 2009–2018
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2022.106872
Abstract: BACKGROUND The use of antiseizure medications (ASMs) in the pediatric population is poorly studied. The purpose of this study was to investigate changes in the use of ASMs in children and adolescents compared to adults,… read more here.
Keywords: children adolescents; year; antiseizure medications; use antiseizure ... See more keywords
Efficacy of Antiseizure Medications in Wolf–Hirschhorn Syndrome
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DOI: 10.1055/a-2077-1988
Abstract: Abstract Background Wolf–Hirschhorn syndrome (WHS) is caused by deletion of the terminal region of chromosome 4 short arm and is frequently associated with intractable epilepsy. Objective This article evaluates the clinical features of epileptic seizures… read more here.
Keywords: antiseizure medications; seizure; whs; age ... See more keywords
Contraception, fecundity, and pregnancy in women with epilepsy: an update on recent literature
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DOI: 10.1097/wco.0000000000001039
Abstract: Purpose of review Caring for women with epilepsy requires specialized knowledge about potential teratogenicity of antiseizure medications, interactions with hormonal contraception, and pregnancy outcomes. Recent findings There has been an improvement in understanding the cognitive… read more here.
Keywords: antiseizure medications; women epilepsy; contraception; pregnancy ... See more keywords
Association between road traffic accidents and drugs belonging to the antiseizure medications class: A pharmacovigilance analysis in VigiBase
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15481
Abstract: Due to their central mechanism of action, antiseizure medications (ASMs) could lead to adverse effects likely to impair driving skills. Their extended use to neuropsychiatric disorders makes it a class of drugs to monitor for… read more here.
Keywords: antiseizure medications; class; road traffic;
Indications and prescribing patterns of antiseizure medications in children in New Zealand.
Sign Up to like & getrecommendations! Published in 2023 at "Developmental medicine and child neurology"
DOI: 10.1111/dmcn.15546
Abstract: AIM To determine indications and prescribing patterns for antiseizure medications (ASMs) in children by age, sex, and socioeconomic status. METHOD This retrospective study searched the New Zealand database of ASM prescriptions dispensed to individuals aged… read more here.
Keywords: antiseizure medications; prescribing patterns; zealand; new zealand ... See more keywords
Early discontinuation of antiseizure medications in neonates with hypoxic–ischemic encephalopathy
Sign Up to like & getrecommendations! Published in 2017 at "Epilepsia"
DOI: 10.1111/epi.13745
Abstract: Neonates with hypoxic–ischemic encephalopathy (HIE) managed with therapeutic hypothermia (TH) often experience acute symptomatic seizures, prompting treatment with antiseizure medications (ASMs). Because the risk of seizure occurrence after hospital discharge is unknown, the optimal ASM… read more here.
Keywords: hypoxic ischemic; neonates hypoxic; early discontinuation; antiseizure medications ... See more keywords