The development of species-specific antisense peptide nucleic acid method for the treatment and detection of viable Salmonella
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e04110
Abstract: Genotypic based detection methods using specific target sites in the pathogen genome can complement phenotypic identification. We report the development of species-specific antisense peptide nucleic acid (PNA) combined with selective and differential enrichment growth conditions… read more here.
Keywords: development species; detection; salmonella; specific antisense ... See more keywords
Antimicrobial activity of antisense peptide–peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw384
Abstract: Background Antisense peptide nucleic acids (PNAs) are synthetic polymers that mimic DNA/RNA and inhibit bacterial gene expression in a sequence-specific manner. Methods To assess activity against non-typeable Haemophilus influenzae (NTHi), we designed six PNA-peptides that… read more here.
Keywords: peptide; pna peptide; pna; peptide nucleic ... See more keywords