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   Articles with "antisense rna" as a keyword



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In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers

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recommendations! Published in 2017 at "Acta Neuropathologica"

DOI: 10.1007/s00401-017-1725-7

Abstract: A growing body of evidence suggests that a loss of chromosome 9 open reading frame 72 (C9ORF72) expression, formation of dipeptide-repeat proteins, and generation of RNA foci contribute to disease pathogenesis in amyotrophic lateral sclerosis… read more here.

Keywords: c9orf72 expansion; rna foci; expansion carriers; rna ... See more keywords
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Antimicrobial antisense RNA delivery to F-pili producing multidrug-resistant bacteria via a genetically engineered bacteriophage.

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recommendations! Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.06.088

Abstract: Multidrug-resistant bacteria are a growing issue worldwide. This study developed a convenient and effective method to downregulate the expression of a specific gene to produce a novel antimicrobial tool using a small (140 nucleotide) RNA… read more here.

Keywords: delivery; rna; antimicrobial antisense; antisense rna ... See more keywords
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HOX transcript antisense RNA (HOTAIR) in cancer.

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recommendations! Published in 2019 at "Cancer letters"

DOI: 10.1016/j.canlet.2019.04.016

Abstract: Long noncoding RNAs (lncRNAs) have emerged as a new family of master regulators of cancer. The lncRNA HOX transcript antisense RNA (HOTAIR) is a prime example of an oncogenic trans-acting lncRNA. The expression of HOTAIR… read more here.

Keywords: hotair; rna hotair; hox transcript; antisense rna ... See more keywords
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Anti-aging and anti-oxidant activities of murine short interspersed nuclear element antisense RNA.

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recommendations! Published in 2021 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2021.174577

Abstract: Short interspersed nuclear elements (SINEs) play a key role in regulating gene expression, and SINE RNAs are involved in age-related diseases. We investigated the anti-aging effects of a genetically engineered murine SINE B1 antisense RNA… read more here.

Keywords: anti aging; rna; antisense rna; b1as rna ... See more keywords
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Therapeutic perceptions in antisense RNA-mediated gene regulation for COVID-19

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recommendations! Published in 2021 at "Gene"

DOI: 10.1016/j.gene.2021.145839

Abstract: COVID-19 was first reported in Wuhan, China, in December 2019. It is widely accepted that the world will not return to its prepandemic normality until safe and effective vaccines are available and a global vaccination… read more here.

Keywords: gene regulation; rna; antisense rna; sars cov ... See more keywords
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The successes and future prospects of the linear antisense RNA amplification methodology

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recommendations! Published in 2018 at "Nature Protocols"

DOI: 10.1038/nprot.2018.011

Abstract: It has been over a quarter of a century since the introduction of the linear RNA amplification methodology known as antisense RNA (aRNA) amplification. Whereas most molecular biology techniques are rapidly replaced owing to the… read more here.

Keywords: methodology; rna amplification; amplification methodology; antisense rna ... See more keywords
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The role of lncRNAs/miRNAs/Sirt1 axis in myocardial and cerebral injury

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recommendations! Published in 2023 at "Cell Cycle"

DOI: 10.1080/15384101.2023.2172265

Abstract: ABSTRACT In recent years, researchers have begun to realize the importance of the role of non-coding RNAs in the treatment of cancer and cardiovascular and neurological diseases. LncRNAs and miRNAs are important non-coding RNAs, which… read more here.

Keywords: antisense rna; transcript; rna; lncrnas mirnas ... See more keywords
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Long noncoding RNA ADIRF antisense RNA 1 upregulates insulin receptor substrate 1 to decrease the aggressiveness of osteosarcoma by sponging microRNA-761

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2019872

Abstract: ABSTRACT An increasing number of studies have supported the critical regulatory actions of long noncoding RNAs (lncRNAs) in osteosarcoma (OS). However, the detailed roles of adipogenesis regulatory factor-antisense RNA 1 (ADIRF-AS1) in OS have not… read more here.

Keywords: adirf as1; rna; long noncoding; antisense rna ... See more keywords
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MicroRNA MiR-490-5p suppresses pancreatic cancer through regulating epithelial-mesenchymal transition via targeting MAGI2 antisense RNA 3

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2024653

Abstract: ABSTRACT Pancreatic cancer with about 5% five-year overall survival rate remains a challenge. Invasion and migration of pancreatic cancer cells are the main factors leading to poor prognosis. MicroRNA-490-5p (miR-490-5p) has anti-cancer effects in a… read more here.

Keywords: mir 490; magi2 as3; antisense rna; pancreatic cancer ... See more keywords
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Klhl14 Antisense RNA is a Target of Key Skeletogenic Transcription Factors in the Developing Intervertebral Disc

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recommendations! Published in 2019 at "SPINE"

DOI: 10.1097/brs.0000000000002827

Abstract: Study Design. RNA in situ hybridization (RISH) allows for validation and characterization of the long noncoding (lnc) natural antisense RNA (NAT) Klhl14as in the embryonic murine intervertebral disc (IVD) in the context of loss-of-function mutants… read more here.

Keywords: antisense; antisense rna; pax1 pax9; transcription factors ... See more keywords
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Prognostic value of lncRNA FEZF1 antisense RNA 1 over-expression in oncologic outcomes of patients with solid tumors

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recommendations! Published in 2019 at "Medicine"

DOI: 10.1097/md.0000000000015982

Abstract: Abstract Background: FEZ family zinc finger 1 antisense RNA 1 (FEZF1-AS1), as a novel lncRNA, was reported to be up-regulated in various cancers and involved in tumor progression. This study systematically assessed the prognostic value… read more here.

Keywords: expression; prognostic value; fezf1 as1; solid tumors ... See more keywords