Tailoring the crystal size distribution of an active pharmaceutical ingredient by continuous antisolvent crystallization in a planar oscillatory flow crystallizer
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Research and Design"
DOI: 10.1016/j.cherd.2021.08.030
Abstract: Abstract An active pharmaceutical ingredient is currently produced in a traditional batch antisolvent crystallization process. Although well-established, this process lacks flexibility to control the crystal size distribution (CSD). Therefore, a new process was developed to… read more here.
Keywords: planar; antisolvent crystallization; crystal size; pharmaceutical ingredient ... See more keywords
Optimization of the process of antisolvent crystallization of carbonized ammonia with a low carbon-to-nitrogen ratio
Sign Up to like & getrecommendations! Published in 2017 at "Fuel Processing Technology"
DOI: 10.1016/j.fuproc.2016.03.012
Abstract: Abstract To address existing problems with carbon capture by ammonia, antisolvent crystallization using ethanol was used to promote crystallization of the carbonized ammonia solution with a low carbon-to-nitrogen ratio. This crystallization process reduced the energy… read more here.
Keywords: carbonized ammonia; antisolvent crystallization; crystallization; process ... See more keywords
Combined cooling and antisolvent crystallization of l-asparagine monohydrate
Sign Up to like & getrecommendations! Published in 2018 at "Powder Technology"
DOI: 10.1016/j.powtec.2018.04.038
Abstract: Abstract Combining cooling crystallization and antisolvent crystallization is advantageous as it not only enhances yield but also offers two manipulative variables to exercise greater control on the outcome of a crystallization process. This study investigates… read more here.
Keywords: cooling antisolvent; antisolvent crystallization; combined cooling; asparagine monohydrate ... See more keywords
Investigation of Agglomeration in the Presence of Oiling Out in the Antisolvent Crystallization Process
Sign Up to like & getrecommendations! Published in 2021 at "Industrial & Engineering Chemistry Research"
DOI: 10.1021/acs.iecr.1c00491
Abstract: Oiling out during the crystallization process often generates agglomeration. This research is focused on the control of agglomeration in the antisolvent crystallization of the propylparaben–ethanol... read more here.
Keywords: crystallization process; investigation agglomeration; antisolvent crystallization; crystallization ... See more keywords
Using Amphiphilic Polymer Micelles as the Templates of Antisolvent Crystallization to Produce Drug Nanocrystals
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01792
Abstract: Biocompatible and biodegradable amphiphilic polymeric micelles (PLA-CMCS-g-OA) were prepared by surface grafting of oleic acid and polylactic acid onto carboxymethyl chitosan and were used as templates for the crystallization of camptothecin. The camptothecin (CPT) nanocrystals… read more here.
Keywords: using amphiphilic; amphiphilic polymer; antisolvent crystallization; crystallization ... See more keywords