Prospective Randomized Double-Blind, Placebo Controlled Evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (PRESERVE-1).
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DOI: 10.1016/j.ajog.2020.08.004
Abstract: BACKGROUND Despite expectant management, preeclampsia remote from term usually results in preterm delivery. Antithrombin displays anti-inflammatory and anticoagulant properties and thus may have a therapeutic role treating preterm preeclampsia, a disorder characterized by endothelial dysfunction,… read more here.
Keywords: antithrombin; preterm preeclampsia; recombinant antithrombin; placebo ... See more keywords