Articles with "antithrombin deficiency" as a keyword



Photo from wikipedia

Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism: a case report

Sign Up to like & get
recommendations!
Published in 2017 at "Frontiers of Medicine"

DOI: 10.1007/s11684-017-0553-4

Abstract: Antithrombin and protein C are two crucial members in the anticoagulant system and play important roles in hemostasis. Mutations in SERPINC1 and PROC lead to deficiency or dysfunction of the two proteins, which could result… read more here.

Keywords: antithrombin deficiency; protein activity; deficiency; decreased protein ... See more keywords
Photo from wikipedia

Antithrombin Deficiency Is Associated with Prothrombotic Plasma Fibrin Clot Phenotype

Sign Up to like & get
recommendations!
Published in 2022 at "Thrombosis and Haemostasis"

DOI: 10.1055/s-0043-1768712

Abstract: BACKGROUND  Deficiency of antithrombin increases risk of venous thromboembolism. We hypothesized that antithrombin deficiency affects fibrin clot structure and function. METHODS  We evaluated 148 patients (age: 38 [32-50] years; 70% women) with genetically confirmed antithrombin… read more here.

Keywords: lower antithrombin; antithrombin deficiency; fibrin clot; deficiency ... See more keywords
Photo from wikipedia

Management of antithrombin deficiency: an update for clinicians

Sign Up to like & get
recommendations!
Published in 2019 at "Expert Review of Hematology"

DOI: 10.1080/17474086.2019.1611424

Abstract: ABSTRACT Introduction. Antithrombin is a serpin that inhibits multiple procoagulant serine proteases and acts as an endogenous anticoagulant. Thus, congenital antithrombin deficiency constitutes a major thrombophilic state, the most severe so far. Areas covered. In… read more here.

Keywords: management antithrombin; deficiency update; antithrombin deficiency; update clinicians ... See more keywords
Photo from wikipedia

Evaluation of Acquired Antithrombin Deficiency in Pediatric Patients Supported on Extracorporeal Membrane Oxygenation.

Sign Up to like & get
recommendations!
Published in 2023 at "British journal of clinical pharmacology"

DOI: 10.1111/bcp.15703

Abstract: BACKGROUND AND PURPOSE There remains a paucity of literature regarding best practice for antithrombin (AT) monitoring, dosing, and dose-response in pediatric ECMO patients. EXPERIMENTAL APPROACH We conducted a retrospective cohort study at a quaternary care… read more here.

Keywords: deficiency pediatric; acquired antithrombin; antithrombin deficiency; activity ... See more keywords
Photo from wikipedia

Antithrombin Deficiency Is Associated with a Novel Homozygous Detrimental Mutation in SERPINC1 Gene in a Saudi Female

Sign Up to like & get
recommendations!
Published in 2023 at "Case Reports in Medicine"

DOI: 10.1155/2023/8872346

Abstract: Antithrombin (AT) deficiency is a blood disorder associated with an increased tendency to form thrombosis. Hereditary AT deficiency is frequently caused by mutations in SERPINC1 gene. It is usually inherited as an autosomal dominant with… read more here.

Keywords: serpinc1 gene; antithrombin deficiency; mutation; gene ... See more keywords
Photo from wikipedia

Heparin Resistance due to an Acquired Antithrombin Deficiency in a Patient With Sickle Cell Disease During a Pregnancy Complicated by Bilateral Pulmonary Emboli: A Case Report.

Sign Up to like & get
recommendations!
Published in 2019 at "A&A Practice"

DOI: 10.1213/xaa.0000000000000917

Abstract: We report a 31-year-old woman with sickle beta thalassemia zero who presented at 21 weeks gestational age with multiple bilateral pulmonary emboli and no hemodynamic instability. Acquired antithrombin deficiency was suspected due to a refractory… read more here.

Keywords: acquired antithrombin; report; bilateral pulmonary; antithrombin deficiency ... See more keywords
Photo by nci from unsplash

MPI-CDG with transient hypoglycosylation and antithrombin deficiency

Sign Up to like & get
recommendations!
Published in 2018 at "Haematologica"

DOI: 10.3324/haematol.2018.211326

Abstract: Antithrombin deficiency is a strong risk factor for venous thromboembolism (VTE) whose testing has demonstrated usefulness.[1][1]–[5][2] Most cases of antithrombin deficiency are explained by mutations in SERPINC1 , the gene encoding this anticoagulant, with detection… read more here.

Keywords: transient hypoglycosylation; mpi cdg; hypoglycosylation antithrombin; antithrombin deficiency ... See more keywords