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   Articles with "antithymocyte globulin" as a keyword



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The impact of intestinal microbiota in antithymocyte globulin–based myeloablative allogeneic hematopoietic cell transplantation

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recommendations! Published in 2022 at "Cancer"

DOI: 10.1002/cncr.34091

Abstract: The correlation between intestinal microbiota and clinical outcomes after allogeneic hematopoietic stem cell transplantation (allo‐HCT) has been reported in platforms with T‐cell depletion or postcyclophosphamide‐based graft‐vs‐host disease (GVHD) prophylaxis regimens. It is still unclear whether… read more here.

Keywords: cell; intestinal microbiota; allogeneic hematopoietic; cell transplantation ... See more keywords
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Rabbit antithymocyte globulin dose does not affect response or survival as first-line therapy for acquired aplastic anemia: a multicenter retrospective study

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recommendations! Published in 2018 at "Annals of Hematology"

DOI: 10.1007/s00277-018-3416-4

Abstract: In a prospective randomized study, treatment for aplastic anemia (AA) with rabbit antithymocyte globulin (r-ATG) and cyclosporine showed inferior hematological response and survival in comparison to horse antithymocyte globulin (h-ATG) and cyclosporine. However, h-ATG was… read more here.

Keywords: response; atg; response survival; antithymocyte globulin ... See more keywords
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High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease

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recommendations! Published in 2020 at "Annals of Hematology"

DOI: 10.1007/s00277-020-04347-1

Abstract: Antithymocyte globulin (ATG) reduces severe acute and chronic graft-versus-host disease (GVHD) in allogeneic peripheral blood stem cell transplantation (PBSCT). However, risk factors for severe acute GVHD in PBSCT using ATG remain to be determined. We… read more here.

Keywords: lymphocyte counts; alc atg; versus host; host disease ... See more keywords
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Induction therapy of basiliximab versus antithymocyte globulin in renal allograft: a systematic review and meta-analysis

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recommendations! Published in 2017 at "Clinical and Experimental Nephrology"

DOI: 10.1007/s10157-017-1480-z

Abstract: ObjectiveThe aim of this meta-analysis was to evaluate the efficacy of basiliximab versus antithymocyte globulin for induction therapy in renal allograft.MethodsMedline (PubMed), Embase, Ovid, Cochrane, and the Chinese Biomedical Literature databases were searched to identify… read more here.

Keywords: induction therapy; rate; antithymocyte globulin; therapy ... See more keywords
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Outcomes and mutational analysis of patients with lower-risk non-del5q myelodysplastic syndrome treated with antithymocyte globulin with or without ciclosporine A.

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recommendations! Published in 2018 at "Leukemia research"

DOI: 10.1016/j.leukres.2018.05.007

Abstract: Immunosuppressive treatment is a disease-modifying therapy for lower-risk myelodysplastic syndromes (MDS). However, IST is relatively rarely used and long-term outcomes of patients are seldom reported. We retrospectively studied outcomes of 20 patients with lower-risk non… read more here.

Keywords: patients lower; risk; lower risk; transfusion ... See more keywords
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Antithymocyte globulin improves GVHD-free and relapse-free survival in unrelated hematopoietic stem cell transplantation

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recommendations! Published in 2019 at "Bone Marrow Transplantation"

DOI: 10.1038/s41409-019-0502-8

Abstract: Antithymocyte globulin (ATG) is an important component of conditioning regimens to prevent graft-versus-host disease (GVHD) in unrelated hematopoietic stem cell transplantation (HSCT), but the optimal dose of ATG remains unknown. We prospectively analyzed 205 unrelated… read more here.

Keywords: year; group; free survival; transplantation ... See more keywords
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Role of antithymocyte globulin in matched sibling donor peripheral blood stem cell transplantation for hematologic malignancies

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recommendations! Published in 2021 at "Medicine"

DOI: 10.1097/md.0000000000024725

Abstract: Abstract Background: High incidence of chronic graft-versus-host disease (GVHD) has been a major drawback of matched sibling donor peripheral blood stem cell transplantation (MSD -PBSCT). This study aimed to investigate the safety and efficacy of… read more here.

Keywords: antithymocyte globulin; matched sibling; gvhd; sibling donor ... See more keywords
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Serial measurement of presepsin, procalcitonin, and C‐reactive protein in the early postoperative period and the response to antithymocyte globulin administration after heart transplantation

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recommendations! Published in 2017 at "Clinical Transplantation"

DOI: 10.1111/ctr.12870

Abstract: Differentiation between systemic inflammatory response syndrome and sepsis in surgical patients is of crucial significance. Procalcitonin (PCT) and C‐reactive protein (CRP) are widely used biomarkers, but PCT becomes compromised after antithymocyte globulin (ATG) administration, and… read more here.

Keywords: administration; presepsin; reactive protein; transplantation ... See more keywords
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Role of antithymocyte globulin in patients with hematologic diseases undergoing umbilical cord blood transplantation: A systematic review and meta‐analysis

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recommendations! Published in 2020 at "Clinical Transplantation"

DOI: 10.1111/ctr.13876

Abstract: The role of antithymocyte globulin (ATG) in patients with hematologic diseases undergoing umbilical cord blood transplantation (UCBT) remains controversial. This systematic review and meta‐analysis was conducted to comprehensively evaluate this issue. PubMed, Embase, and the… read more here.

Keywords: role antithymocyte; patients hematologic; transplantation; diseases undergoing ... See more keywords
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Antithymocyte globulin induction therapy and myocardial complement deposition in pediatric heart transplantation

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recommendations! Published in 2021 at "Pediatric Transplantation"

DOI: 10.1111/petr.13998

Abstract: Antithymocyte globulin (ATG) consists of polyclonal antibodies directed primarily against human T lymphocytes but may contain antibodies with affinity for other tissues in the transplanted organ, resulting in complement (C4d) deposition. This phenomenon has been… read more here.

Keywords: deposition; globulin induction; transplantation antithymocyte; antithymocyte globulin ... See more keywords
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Changes in Sepsis Biomarkers after Immunosuppressant Administration in Transplant Patients

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recommendations! Published in 2021 at "Mediators of Inflammation"

DOI: 10.1155/2021/8831659

Abstract: Sepsis biomarkers change continuously during the postoperative period. We aimed to demonstrate the influence of immunosuppressants after transplantation (Tx) on presepsin, procalcitonin, CRP, white blood cells, and IL-6. A group of 140 patients after major… read more here.

Keywords: sepsis biomarkers; biomarkers immunosuppressant; changes sepsis; presepsin procalcitonin ... See more keywords