GhoT of the GhoT/GhoS toxin/antitoxin system damages lipid membranes by forming transient pores.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.01.067
Abstract: GhoT is a bacterial toxin of the type V toxin/antitoxin system that allows Escherichia coli to reduce its metabolism in response to oxidative and bile stress. GhoT functions by increasing membrane permeability and reducing both… read more here.
Keywords: toxin antitoxin; toxin; forming transient; antitoxin system ... See more keywords
The Haemophilus influenzae HipBA toxin–antitoxin system adopts an unusual three-component regulatory mechanism
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DOI: 10.1107/s205225252200687x
Abstract: The crystal structure of HipAN, an unusual N-terminal component of the HipA toxin from Haemophilus influenzae, was determined at 2.70 Å resolution. A combined study on this unique three-component HipBA toxin–antitoxin system provides further insights into… read more here.
Keywords: toxin antitoxin; component; antitoxin system; hipba toxin ... See more keywords
TisB Protein Protects Escherichia coli Cells Suffering Massive DNA Damage from Environmental Toxic Compounds
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DOI: 10.1128/mbio.00385-22
Abstract: The contribution of toxin-antitoxin systems to the persistence of bacteria to antibiotics has been intensively studied. This is also the case with the E. coli TisB/IstR toxin-antitoxin system, but the contribution of TisB to the… read more here.
Keywords: toxin antitoxin; tisb; antitoxin system; escherichia coli ... See more keywords