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   Articles with "antitoxin system" as a keyword



GhoT of the GhoT/GhoS toxin/antitoxin system damages lipid membranes by forming transient pores.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.01.067

Abstract: GhoT is a bacterial toxin of the type V toxin/antitoxin system that allows Escherichia coli to reduce its metabolism in response to oxidative and bile stress. GhoT functions by increasing membrane permeability and reducing both… read more here.

Keywords: toxin antitoxin; toxin; forming transient; antitoxin system ... See more keywords

Engineered Vibrio natriegens with a Toxin-Antitoxin System for High-Productivity Biotransformation of l-Lysine to Cadaverine.

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recommendations! Published in 2025 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.4c12616

Abstract: Vibrio natriegens, a fast-growing bacterium, is an emerging chassis of next-generation industrial biotechnology capable of thriving under open and continuous culture conditions. Cadaverine, a valuable industrial C5 platform chemical, has various chemical and biological activities.… read more here.

Keywords: toxin antitoxin; antitoxin system; cadaverine; lysine ... See more keywords

The Haemophilus influenzae HipBA toxin–antitoxin system adopts an unusual three-component regulatory mechanism

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recommendations! Published in 2022 at "IUCrJ"

DOI: 10.1107/s205225252200687x

Abstract: The crystal structure of HipAN, an unusual N-terminal component of the HipA toxin from Haemophilus influenzae, was determined at 2.70 Å resolution. A combined study on this unique three-component HipBA toxin–antitoxin system provides further insights into… read more here.

Keywords: toxin antitoxin; component; antitoxin system; hipba toxin ... See more keywords

TisB Protein Protects Escherichia coli Cells Suffering Massive DNA Damage from Environmental Toxic Compounds

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recommendations! Published in 2022 at "mBio"

DOI: 10.1128/mbio.00385-22

Abstract: The contribution of toxin-antitoxin systems to the persistence of bacteria to antibiotics has been intensively studied. This is also the case with the E. coli TisB/IstR toxin-antitoxin system, but the contribution of TisB to the… read more here.

Keywords: toxin antitoxin; tisb; antitoxin system; escherichia coli ... See more keywords

Toxin-antitoxin system gene mutations driving Mycobacterium tuberculosis transmission revealed by whole genome sequencing

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recommendations! Published in 2024 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2024.1398886

Abstract: Background The toxin-antitoxin (TA) system plays a vital role in the virulence and pathogenicity of Mycobacterium tuberculosis (M. tuberculosis). However, the regulatory mechanisms and the impact of gene mutations on M. tuberculosis transmission remain poorly… read more here.

Keywords: toxin antitoxin; transmission; antitoxin system; tuberculosis ... See more keywords