Synthesis, antitubercular evaluation, and molecular docking studies of hybrid pyridinium salts derived from isoniazid
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22039
Abstract: In the quest to develop potent inhibitors for Mycobacterium tuberculosis, novel isoniazid‐based pyridinium salts were designed, synthesized, and tested for their antimycobacterial activities against the H37Rv strain of Mycobacterium tuberculosis using rifampicin as a standard.… read more here.
Keywords: derived isoniazid; synthesis antitubercular; pyridinium salts; antitubercular evaluation ... See more keywords
Synthesis and antitubercular evaluation of imidazo[2,1-b][1,3,4]thiadiazole derivatives
Sign Up to like & getrecommendations! Published in 2017 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2013.01.001
Abstract: Abstract In the present study, a series of imidazo[2,1-b][1,3,4]thiadiazole derivatives 5(a–j) were synthesized and characterized by IR, 1H NMR, 13C NMR and mass spectral technique. The compounds were evaluated for their in vitro antitubercular activity… read more here.
Keywords: imidazo thiadiazole; antitubercular evaluation; synthesis antitubercular; thiadiazole derivatives ... See more keywords