Detection of resistance to fluoroquinolones and injectable drugs among antituberculosis drugs by allele-specific primer extension on a microsphere-based platform.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2017.11.007
Abstract: Molecular drug susceptibility testing (DST) for antituberculosis drugs is important for improving the efficacy of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) treatment. In this study, we developed a molecular high-throughput assay system based… read more here.
Keywords: 100 100; resistance; antituberculosis drugs; tag aspe ... See more keywords
Comprehensive Substrate Characterization of 22 Antituberculosis Drugs for Multiple Solute Carrier (SLC) Uptake Transporters In Vitro
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DOI: 10.1128/aac.00512-18
Abstract: The substrate potentials of antituberculosis drugs on solute carrier (SLC) transporters are not well characterized to date, despite a well-established understanding of their drug dispositions and pharmacokinetics. In this study, we investigated comprehensively the substrate… read more here.
Keywords: solute carrier; drug; antituberculosis drugs; carrier slc ... See more keywords
Safety Evaluation of Antituberculosis Drugs During Pregnancy: A Systematic Review and Meta-Analysis
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DOI: 10.3389/fsurg.2022.871321
Abstract: Background Pregnant women are a common group of people with tuberculosis,especially in patients infected with HIV at the same time. Antituberculosis drug prophylaxis is effective in reducing tuberculosis infection in pregnant women and fetuses after… read more here.
Keywords: drugs pregnancy; antituberculosis drugs; meta analysis; antituberculosis ... See more keywords
Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles
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DOI: 10.3390/ijms24043383
Abstract: Precision medicine gives individuals tailored medical treatment, with the genotype determining the therapeutic strategy, the appropriate dosage, and the likelihood of benefit or toxicity. Cytochrome P450 (CYP) enzyme families 1, 2, and 3 play a… read more here.
Keywords: cyp; antituberculosis drugs; antimalarial antituberculosis; cytochrome p450 ... See more keywords
Propolis modulates cellular biochemistry, antioxidants, cytokine profile, histological and ultra-morphological status against antituberculosis drugs induced hepatic injury
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DOI: 10.4103/1995-7645.246337
Abstract: Objective: To evaluate hepatic injury induced by antituberculosis drugs (ATDs) when administered orally for 2, 4, 6 and 8 weeks and the therapeutic potential of propolis (bee hive product) against ATDs induced hepatic injury. Methods:… read more here.
Keywords: biochemistry; propolis; antituberculosis drugs; induced hepatic ... See more keywords
Uric acid levels in patients on antituberculosis drugs in the southwest Region of Cameroon
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DOI: 10.4103/ijmy.ijmy_161_17
Abstract: Background: Antituberculosis drugs (ATDs) efficiently combat Mycobacterium tuberculosis either through direct molecular interactions or those of its metabolites. However, a variety of adverse effects have been reported, leading to frequent interruptions of treatment. To investigate… read more here.
Keywords: region cameroon; uric acid; southwest region; treatment ... See more keywords