Synthesis of aspirin-curcumin mimic conjugates of potential antitumor and anti-SARS-CoV-2 properties
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic Chemistry"
DOI: 10.1016/j.bioorg.2021.105466
Abstract: Series of piperidone-salicylate conjugates were synthesized through the reaction of 3E,5E-bis(arylidene)-4-piperidones with the appropriate acid chloride of acetylsalicylate in the presence of triethylamine. All the synthesized conjugates reveal antiproliferative properties against A431 (squamous skin) cancer… read more here.
Keywords: antitumor anti; anti sars; cancer; sars cov ... See more keywords
Low molecular weight heparin-based reduction-sensitive nanoparticles for antitumor and anti-metastasis of orthotopic breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Biomaterials science"
DOI: 10.1039/c8bm00486b
Abstract: Tumor metastasis has become a major obstacle for the clinical treatment of malignant breast cancer. Thus, a delivery system capable of both antitumor and anti-metastasis efficacy is desired. In this work, a low molecular weight… read more here.
Keywords: breast; dox cllhc2; antitumor anti; anti metastasis ... See more keywords