Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8+ T Cells
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DOI: 10.1002/advs.202207499
Abstract: Natural killer (NK) cells not only are innate effector lymphocytes that directly participate in tumor surveillance but are also essential helpers in the antitumor CD8+ T‐cell response. However, the molecular mechanisms and potential checkpoints regulating… read more here.
Keywords: cell; response; antitumor cd8; helper functions ... See more keywords
Antitumor PD-1- CD8+ T-cell Subsets Expand upon Anti-PD-1/TIM3 Therapy.
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DOI: 10.1158/2159-8290.cd-rw2019-007
Abstract: ICB acts onTcf7/TCF1-expressing memory precursor-like PD-1- CD8+ TILs that are needed for ICB efficacy. read more here.
Keywords: cd8 cell; antitumor cd8; subsets expand; cd8 ... See more keywords