Genetically engineering glycolysis in T cells increases their antitumor function
Sign Up to like & getrecommendations! Published in 2024 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2023-008434
Abstract: Background T cells play a central role in the antitumor response. However, they often face numerous hurdles in the tumor microenvironment, including the scarcity of available essential metabolites such as glucose and amino acids. Moreover,… read more here.
Keywords: antitumor function; cell; genetically engineering; glycolysis ... See more keywords
Assessment of antitumor function of NK cells expanded with exosomes from K562.mb21 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.7_suppl.132
Abstract: 132Background: NK cells can kill malignant cells to provide innate immunity against tumors. Due to their low abundance in blood, a focus is to expand NK cells ex vivo having enhanced anti-tumor cyt... read more here.
Keywords: assessment antitumor; exosomes k562; expanded exosomes; function cells ... See more keywords