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   Articles with "antitumoral activity" as a keyword



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Antiangiogenic and antitumoral activity of LQFM126 prototype against B16F10 melanoma cells.

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recommendations! Published in 2020 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2020.109127

Abstract: Inhibition of mouse double minute 2 homolog (MDM2)-p53 interaction and reactivation of p53 signaling have been explored as effective anticancer therapeutic strategy. The potent and specific antitumor activity shown by Nutlins, first class of MDM2-p53… read more here.

Keywords: lqfm126; activity; antitumoral activity; melanoma cells ... See more keywords
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Eugenia uniflora L. seed and pulp extracts: phytochemical profile, cytotoxic potential, antitumoral activity, and α-amylase and α-glucosidase inhibition capacity.

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recommendations! Published in 2022 at "Natural product research"

DOI: 10.1080/14786419.2022.2153128

Abstract: In this study, phytochemical profiling, cytotoxic potential, antitumoral activity, and α-amylase and α-glucosidase inhibition capacity of extracts of seed and pulp of Eugenia uniflora L. fruits were investigated. The extracts were obtained using a cellulase… read more here.

Keywords: amylase glucosidase; antitumoral activity; potential antitumoral; cytotoxic potential ... See more keywords
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Genetic and Biochemical Characterization of an Exopolysaccharide With in vitro Antitumoral Activity Produced by Lactobacillus fermentum YL-11

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recommendations! Published in 2019 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2019.02898

Abstract: In the present study, the whole genome sequence of Lactobacillus fermentum YL-11, a novel exopolysaccharide (EPS)-producing lactic acid bacteria (LAB) strain isolated from fermented milk, was determined. Genetic information and the synthetic mechanism of the… read more here.

Keywords: lactobacillus fermentum; biochemical characterization; antitumoral activity; characterization exopolysaccharide ... See more keywords
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EGFR-Specific Tyrosine Kinase Inhibitor Modifies NK Cell-Mediated Antitumoral Activity against Ovarian Cancer Cells

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recommendations! Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20194693

Abstract: The adverse prognosis of most patients with ovarian cancer is related to recurrent disease caused by resistance to chemotherapeutic and targeted therapeutics. Besides their direct activity against tumor cells, monoclonal antibodies and tyrosine kinase inhibitors… read more here.

Keywords: antitumoral activity; ovarian cancer; cancer cells; cancer ... See more keywords
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A New Manganese Superoxide Dismutase Mimetic Improves Oxaliplatin-Induced Neuropathy and Global Tolerance in Mice

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232112938

Abstract: Reactive oxygen species (ROS) are produced by every aerobic cell during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. Superoxide Dismutases (SOD) are antioxidant proteins that convert superoxide… read more here.

Keywords: oxaliplatin; antitumoral activity; tolerance; oxaliplatin induced ... See more keywords
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Immunomodulatory and Antitumoral Activity of Gold Nanoparticles Synthesized by Red Algae Aqueous Extracts

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recommendations! Published in 2022 at "Marine Drugs"

DOI: 10.3390/md20030182

Abstract: This study reports on the green and cost-efficient synthesis of gold nanoparticles from three different red algae extracts. The nanoparticles synthesized were fully characterized by UV-Vis spectroscopy, HRTEM, and Z-potential. Relevant components occurring in the… read more here.

Keywords: nanoparticles synthesized; gold nanoparticles; antitumoral activity; immunomodulatory antitumoral ... See more keywords

Portuguese Propolis Antitumoral Activity in Melanoma Involves ROS Production and Induction of Apoptosis

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recommendations! Published in 2022 at "Molecules"

DOI: 10.3390/molecules27113533

Abstract: Melanoma is the most aggressive and life-threatening skin cancer type. The melanoma genome is the most frequently mutated, with the BRAF mutation present in 40–60% of melanoma cases. BRAF-mutated melanomas are characterized by a higher… read more here.

Keywords: melanoma; antitumoral activity; portuguese propolis; activity ... See more keywords