The T cell activating properties and antitumour activity of Staphylococcal Enterotoxin-like Q
Sign Up to like & getrecommendations! Published in 2019 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-019-00614-9
Abstract: Staphylococcal enterotoxins (SEs), as typical superantigens, exhibit promising antitumour activity in the clinic, but their unavoidable side effects related to fever and emesis seriously limit their application for the treatment of malignant tumours. Fortunately, the… read more here.
Keywords: staphylococcal enterotoxin; antitumour activity; selq; activity ... See more keywords
Development of a protein-based system for transient epigenetic repression of immune checkpoint molecule and enhancement of antitumour activity of natural killer cells
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-019-0708-y
Abstract: Background Immune checkpoint blockade (ICB) therapy improved the prognosis of cancer patients, but general administration of ICBs occasionally induces side effects that include immune-related adverse events and tumour hyper-progression. Here, we established a protein-based system,… read more here.
Keywords: protein based; immune checkpoint; system; antitumour activity ... See more keywords
Localized argyria: troublesome side‐effect of acupuncture
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.14526
Abstract: events of PD-1 immunotherapy are being increasingly reported and characterized. Since our initial publication, additional cases of eruptive KAs have been reported, supporting its status as an associated adverse event. It is encouraging to see… read more here.
Keywords: localized argyria; antitumour activity; troublesome side; effect acupuncture ... See more keywords
siRNA-mediated inactivation of HER3 improves the antitumour activity and sensitivity of gefitinib in gastric cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17526
Abstract: The human EGFR family consists of four type-1 transmembrane tyrosine kinase receptors: HER1 (EGFR, ErbB1), HER2 (Neu, ErbB2), HER3 (ErbB3), and HER4 (ErbB4). HER3 can dimerize with EGFR, HER2 and even c-Met and likely plays… read more here.
Keywords: antitumour activity; activity sensitivity; cancer; her3 ... See more keywords
Tetracenomycin X Exerts Antitumour Activity in Lung Cancer Cells through the Downregulation of Cyclin D1
Sign Up to like & getrecommendations! Published in 2019 at "Marine Drugs"
DOI: 10.3390/md17010063
Abstract: Tetracenomycin X (Tcm X) has been reported to have antitumour activity in various cancers, but there have not been any studies on its activity with respect to lung cancer to date. Therefore, this study aims… read more here.
Keywords: cyclin; activity; antitumour activity; lung cancer ... See more keywords
An Overview of Antitumour Activity of Polysaccharides
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27228083
Abstract: Cancer incidence and mortality are rapidly increasing worldwide; therefore, effective therapies are required in the current scenario of increasing cancer cases. Polysaccharides are a family of natural polymers that hold unique physicochemical and biological properties,… read more here.
Keywords: antitumour activity; overview antitumour; activity polysaccharides; activity ... See more keywords
HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14061201
Abstract: Mebendazole and other benzimidazole antihelmintics, such as albendazole, fenbendazole, or flubendazole, have been shown to possess antitumour activity, primarily due to their microtubule-disrupting activity. However, the extremely poor water-solubility of mebendazole and other benzimidazoles, resulting… read more here.
Keywords: antitumour activity; mebendazole; systemic administration; activity ... See more keywords