Impact of oncogenic pathways on evasion of antitumour immune responses
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Cancer"
DOI: 10.1038/nrc.2017.117
Abstract: Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a… read more here.
Keywords: pathways evasion; immune responses; evasion antitumour; impact oncogenic ... See more keywords
A bioorthogonal system reveals antitumour immune function of pyroptosis
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2079-1
Abstract: Bioorthogonal chemistry capable of operating in live animals is needed to investigate biological processes such as cell death and immunity. Recent studies have identified a gasdermin family of pore-forming proteins that executes inflammasome-dependent and -independent… read more here.
Keywords: system; pyroptosis; bioorthogonal system; gasdermin ... See more keywords
The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/9721028
Abstract: Background Evaluate the effect of the miRNA-106a/20b on the efficacy of DCs pulsed with GSCs in activating GSC-specific T cell responses. Methods We cultured GSCs and prepared GSC antigen lysates by apoptosis. Then, immature DCs… read more here.
Keywords: 106a 20b; antitumour immune; immune responses; mir 106a ... See more keywords