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Published in 2017 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.08.020
Abstract: Saw-scaled vipers (genus Echis) are one of the leading causes of snakebite morbidity and mortality in parts of Sub-Saharan Africa, the Middle East, and vast regions of Asia, constituting a public health burden exceeding that…
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Keywords:
cross reactivity;
human plasma;
narrow taxonomic;
antivenom ... See more keywords
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2
Published in 2022 at "Clinical Toxicology"
DOI: 10.1080/15563650.2022.2041200
Abstract: Abstract Background and aims In Mainland China and Hong Kong, health authorities utilize Agkistrodon halys antivenom in the treatment of patients who sustained bites from green pit vipers. However, the treatment benefit of Agkistrodon halys…
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Keywords:
agkistrodon halys;
antivenom;
halys antivenom;
green pit ... See more keywords
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Published in 2022 at "Clinical Toxicology"
DOI: 10.1080/15563650.2022.2042550
Abstract: Abstract Introduction Late hemotoxicity is common following rattlesnake envenomation treated with crotalidae immune polyvalent Fab (ovine) (FabAV). Initial clinical trials showed crotalidae immune F(ab')2 (equine) (Fab2AV) to be superior to FabAV in preventing late hemotoxicity,…
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Keywords:
envenomation;
hemotoxicity;
late hemotoxicity;
crotalidae immune ... See more keywords
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Published in 2020 at "Journal of veterinary emergency and critical care"
DOI: 10.1111/vec.12978
Abstract: OBJECTIVES To evaluate the in vitro efficacy of specific Daboia (Vipera) palaestinae (Dp) antivenom or fresh frozen plasma (FFP) against Dp venom-induced hemostatic changes DESIGN: In vitro study. SETTING Laboratory of a university referral hospital.…
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Keywords:
efficacy specific;
antivenom;
venom induced;
specific antivenom ... See more keywords
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Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008109
Abstract: For most antivenoms there is little information from clinical studies to infer the relationship between dose and efficacy or dose and toxicity. Antivenom dose-finding studies usually recruit too few patients (e.g. fewer than 20) relative…
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Keywords:
model based;
dose finding;
based adaptive;
antivenom ... See more keywords
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Published in 2022 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010915
Abstract: Background Despite domestic production of antivenoms in the Association of Southeast Asian Nations (ASEAN) countries, not all victims with snakebite envenomings indicated for antivenom received the appropriate or adequate effective dose of antivenom due to…
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Keywords:
asean countries;
improving access;
antivenom;
access ... See more keywords
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Published in 2022 at "Toxins"
DOI: 10.3390/toxins14070481
Abstract: In India, polyvalent antivenom is the mainstay treatment for snakebite envenoming. Due to batch-to-batch variation in antivenom production, manufacturers have to estimate its efficacy at each stage of IgG purification using the median effective dose…
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Keywords:
venom;
antivenom efficacy;
echis carinatus;
efficacy ... See more keywords
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Published in 2022 at "Toxins"
DOI: 10.3390/toxins14070505
Abstract: Daboia siamensis (Russell’s viper) is a highly venomous and medically important snake in China, as well as much of Asia. There is minimal information on the pharmacological activity of the venom of the Chinese species,…
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Keywords:
siamensis;
venom;
russell viper;
antivenom ... See more keywords
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Published in 2023 at "Toxins"
DOI: 10.3390/toxins15040265
Abstract: Snakebite envenoming is a neglected tropical disease prevalent in South Asia. In Pakistan, antivenoms are commonly imported from India despite the controversy over their effectiveness. To solve the problem, the locals have developed the Pakistani…
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Keywords:
viper antivenom;
neutralization;
pakistani viper;
antivenom pvav ... See more keywords
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Published in 2023 at "Tropical Medicine and Infectious Disease"
DOI: 10.3390/tropicalmed8060302
Abstract: Morocco is one of the richest countries in biodiversity in the Mediterranean region, especially in its ophidian fauna. In total, there are eight species of venomous snakes, with seven belonging to the Viperidae family, responsible…
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Keywords:
insight toxicological;
moroccan vipers;
inoserp mena;
neutralization ... See more keywords