Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112085
Abstract: HIV-1 CA is involved in different stages of the viral replication cycle, performing essential roles in both early (uncoating, reverse transcription, nuclear import, integration) and late events (assembly). Recent efforts have demonstrated HIV-1 CA protein… read more here.
Keywords: design synthesis; phenyl triazole; phenylalanine derivatives; triazole phenylalanine ... See more keywords
The influence of some promising fused azaisocytosine‐containing congeners on zebrafish (Danio rerio) embryos/larvae and their antihaemolytic, antitumour and antiviral activities
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2019.02.033
Abstract: ABSTRACT The present study was aimed at broadening the profile of toxicity and biological activity of promising fused azaisocytosine‐containing congeners (I‐VI) possessing medical applicability and important pharmacokinetic properties. For this purpose, the in vivo zebrafish… read more here.
Keywords: containing congeners; azaisocytosine containing; promising fused; embryos larvae ... See more keywords
Molecular docking and antiviral activities of plant derived compounds against zika virus.
Sign Up to like & getrecommendations! Published in 2020 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2020.104540
Abstract: Zika virus (ZIKV), a recently emerged pathogen of the genus flavivirus causes Guillain-Barré syndrome and microcephaly in fetus and newborns from infected mothers. Until date, there are no licensed vaccine or approved drug to treat… read more here.
Keywords: docking antiviral; activities plant; zika virus; molecular docking ... See more keywords
Synthesis of Selenoesters via Aldol Condensation and/or Conjugate Reduction and Their Antiviral Activities
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06784
Abstract: A variety of unsaturated selenoesters (including phenolic ones) were produced in good to high yields and with high E/Z ratios using TiCl4-promoted aldol condensation between Se-phenyl selenoacetate and their respective aldehydes without aqueous workup. A… read more here.
Keywords: antiviral activities; conjugate; conjugate reduction; reduction ... See more keywords
Photocatalytic-Driven Antiviral Activities of Heterostructured BiOCl0.2Br0.8 – BiOBr Semiconductors
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.3c10310
Abstract: Numerous methods for eliminating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are being extensively examined in recent years as a result of the COVID-19 pandemic and its adverse effects on society. Photocatalysis is among the… read more here.
Keywords: biocl0 2br0; photocatalytic driven; antiviral activities; driven antiviral ... See more keywords
Antiviral activities of natural compounds and ionic liquids to inhibit the Mpro of SARS-CoV-2: a computational approach
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra08604a
Abstract: The recalcitrant spread of the COVID-19 pandemic produced by the novel coronavirus SARS-CoV-2 is one of the most destructive occurrences in history. Despite the availability of several effective vaccinations and their widespread use, this line… read more here.
Keywords: mpro sars; activities natural; natural compounds; antiviral activities ... See more keywords
Comparison of different methods for extraction of Cinnamomi ramulus: yield, chemical composition and in vitro antiviral activities
Sign Up to like & getrecommendations! Published in 2017 at "Natural Product Research"
DOI: 10.1080/14786419.2017.1299724
Abstract: Abstract Hydrodistillation (HD), supercritical fluid extraction (SFE) and reflux extraction (RE) were applied to obtain Cinnamomi ramulus extracts. The yields, chemical compositions and antiviral activities of the extracts were investigated. Extracts were analysed using gas… read more here.
Keywords: extraction; cinnamomi ramulus; different methods; comparison different ... See more keywords
Antiviral activities of mycophenolic acid and IMD‐0354 against SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2020 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12828
Abstract: In this study, the anti–severe acute respiratory syndrome coronavirus‐2 (anti‐SARS‐CoV‐2) activity of mycophenolic acid (MPA) and IMD‐0354 was analyzed. These compounds were chosen based on their antiviral activities against other coronaviruses. Because they also inhibit… read more here.
Keywords: activities mycophenolic; mycophenolic acid; anti sars; sars cov ... See more keywords
Antiviral activities of Clinacanthus nutans (Burm.f.) Lindau extract against Cyprinid herpesvirus 3 in koi (Cyprinus carpio koi).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of fish diseases"
DOI: 10.1111/jfd.12757
Abstract: Cyprinid herpesvirus 3 (CyHV-3) or koi herpesvirus (KHV) is a virulent viral infection in common carp and koi. The disease has caused global epizootic and economic loss in fish aquaculture and in the wild. Clinacanthus… read more here.
Keywords: cyprinid herpesvirus; burm lindau; nutans burm; herpesvirus ... See more keywords
Investigating the in vitro antibacterial, antibiofilm, antioxidant, anticancer and antiviral activities of zinc oxide nanoparticles biofabricated from Cassia javanica
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0310927
Abstract: It is thought to be risk-free, environmentally benign, and safe for biological processes to produce zinc oxide nanoparticles from renewable resources. This study examined Cassia javanica’s ability to create ZnONPs. The generated ZnONPs were analyzed… read more here.
Keywords: spectroscopy; zinc oxide; antiviral activities; znonps ... See more keywords
Design, synthesis, antiviral activities of ferulic acid derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1133655
Abstract: A series of novel ferulic acid derivatives were designed and synthesized, and the twenty-one compounds were evaluated for their antiviral activities against Respiratory syncytial virus (RSV), herpes simplex virus type 1 (HSV-1), and enterovirus type… read more here.
Keywords: effect; antiviral activities; virus; type ... See more keywords