Development and in vitro antiviral activity of ivermectin liposomes as a potential drug carrier system
Sign Up to like & getrecommendations! Published in 2024 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202300708
Abstract: This study aimed to assess and compare diverse formulations of ivermectin‐loaded liposomes, employing lipid film hydration and ethanol injection methods. Three lipids (DOPC, SPC, and DSPC) were used in predetermined molar ratios. A total of… read more here.
Keywords: development vitro; ivermectin; drug; antiviral activity ... See more keywords
Synthesis and antiviral activity of novel imidazo[2,1‐b]thiazoles coupled with morpholine and thiomorpholines
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.4778
Abstract: Herein described the synthesis and antiviral evaluation of a novel series of morpholine and thio‐morpholine coupled imidazo[2,1‐b]thiazoles. The three‐step reaction sequence involving the condensation of 1,3‐dichloroacetone with thiourea followed by coupling with morpholine and thiomorpholine… read more here.
Keywords: synthesis antiviral; imidazo thiazoles; antiviral activity; novel ... See more keywords
Antiviral activity of Carbenoxolone disodium against dengue virus infection
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24571
Abstract: As one of the most important mosquito‐borne viral diseases, dengue infection is now becoming a global concern due to its rapid spread and rise in incidence. Currently, there is no approved vaccine or effective antiviral… read more here.
Keywords: denv; antiviral activity; infection; dengue ... See more keywords
Synergistic antiviral activity of Sofosbuvir and type‐I interferons (α and β) against Zika virus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24932
Abstract: Zika virus (ZIKV) is transmitted by mosquitoes and causes Dengue‐like illness, neurological symptoms such as Guillain‐Barré Syndrome and microcephaly in children born to infected pregnant mothers. Recently, the World Health Organization (WHO) declared ZIKV infection… read more here.
Keywords: combination; antiviral activity; sofosbuvir; zikv ... See more keywords
In vitro activity of itraconazole against SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26917
Abstract: Although vaccination campaigns are currently being rolled out to prevent coronavirus disease (COVID‐19), antivirals will remain an important adjunct to vaccination. Antivirals against coronaviruses do not exist, hence global drug repurposing efforts have been carried… read more here.
Keywords: itraconazole itraconazole; antiviral activity; activity itraconazole; sars cov ... See more keywords
Recent progress in the antiviral activity and mechanism study of pentacyclic triterpenoids and their derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Medicinal Research Reviews"
DOI: 10.1002/med.21484
Abstract: Viral infections cause many serious human diseases with high mortality rates. New drug‐resistant strains are continually emerging due to the high viral mutation rate, which makes it necessary to develop new antiviral agents. Compounds of… read more here.
Keywords: pentacyclic triterpenoids; activity mechanism; antiviral activity; progress antiviral ... See more keywords
Carnosine exhibits significant antiviral activity against Dengue and Zika virus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Peptide Science"
DOI: 10.1002/psc.3196
Abstract: Dengue virus (DENV) and Zika virus (ZIKV) are flaviviruses transmitted to humans by their common vector, Aedes mosquitoes. DENV infection represents one of the most widely spread mosquito‐borne diseases whereas ZIKV infection occasionally re‐emerged in… read more here.
Keywords: carnosine; antiviral activity; zika virus; dengue ... See more keywords
SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL 3-SUBSTITUTED PYRAZOLINIUM SALTS
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/6071
Abstract: For the first time, convenient methods for the preparation of pyrazoline N-alkylidene salts based on terpene (camphor, camphorquinone, carvone) ketones, cage (adamantanone and norcamphor) ketones, and natural aldehydes (carvone and myrtenal) allowing the isolation of… read more here.
Keywords: activity novel; antiviral activity; pyrazolinium salts; activity ... See more keywords
Repositioning of Antibiotics in the Treatment of Viral Infections
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DOI: 10.1007/s00284-024-03948-7
Abstract: Drug repurposing, also known as drug repositioning, is a currently tested approach by which new uses are being assigned for already tested drugs. In this case there are antibiotics that are used to combat bacterial… read more here.
Keywords: antiviral activity; repositioning antibiotics; treatment viral; viral infections ... See more keywords
Tailoring acyclovir prodrugs with enhanced antiviral activity: rational design, synthesis, human plasma stability and in vitro evaluation
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2590-y
Abstract: Bile acid prodrugs have served as a viable strategy for refining the pharmaceutical profile of parent drugs through utilizing bile acid transporters. A series of three ester prodrugs of the antiherpetic drug acyclovir (ACV) with… read more here.
Keywords: acv; hsv; plasma stability; antiviral activity ... See more keywords
Antiviral activity of Cynodon dactylon on white spot syndrome virus (WSSV)-infected shrimp: an attempt to mitigate risk in shrimp farming
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture International"
DOI: 10.1007/s10499-020-00553-w
Abstract: White spot syndrome virus (WSSV) is the most contagious pathogen causing huge economic losses in the shrimp industry worldwide. Several medicinal plants are known to have antiviral activity through the inhibition of viral diseases in… read more here.
Keywords: dactylon; white spot; antiviral activity; spot syndrome ... See more keywords