Antiviral activity of Carbenoxolone disodium against dengue virus infection
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DOI: 10.1002/jmv.24571
Abstract: As one of the most important mosquito‐borne viral diseases, dengue infection is now becoming a global concern due to its rapid spread and rise in incidence. Currently, there is no approved vaccine or effective antiviral… read more here.
Keywords: denv; antiviral activity; infection; dengue ... See more keywords
Synergistic antiviral activity of Sofosbuvir and type‐I interferons (α and β) against Zika virus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24932
Abstract: Zika virus (ZIKV) is transmitted by mosquitoes and causes Dengue‐like illness, neurological symptoms such as Guillain‐Barré Syndrome and microcephaly in children born to infected pregnant mothers. Recently, the World Health Organization (WHO) declared ZIKV infection… read more here.
Keywords: combination; antiviral activity; sofosbuvir; zikv ... See more keywords
In vitro activity of itraconazole against SARS‐CoV‐2
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DOI: 10.1002/jmv.26917
Abstract: Although vaccination campaigns are currently being rolled out to prevent coronavirus disease (COVID‐19), antivirals will remain an important adjunct to vaccination. Antivirals against coronaviruses do not exist, hence global drug repurposing efforts have been carried… read more here.
Keywords: itraconazole itraconazole; antiviral activity; activity itraconazole; sars cov ... See more keywords
Recent progress in the antiviral activity and mechanism study of pentacyclic triterpenoids and their derivatives
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DOI: 10.1002/med.21484
Abstract: Viral infections cause many serious human diseases with high mortality rates. New drug‐resistant strains are continually emerging due to the high viral mutation rate, which makes it necessary to develop new antiviral agents. Compounds of… read more here.
Keywords: pentacyclic triterpenoids; activity mechanism; antiviral activity; progress antiviral ... See more keywords
Carnosine exhibits significant antiviral activity against Dengue and Zika virus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Peptide Science"
DOI: 10.1002/psc.3196
Abstract: Dengue virus (DENV) and Zika virus (ZIKV) are flaviviruses transmitted to humans by their common vector, Aedes mosquitoes. DENV infection represents one of the most widely spread mosquito‐borne diseases whereas ZIKV infection occasionally re‐emerged in… read more here.
Keywords: carnosine; antiviral activity; zika virus; dengue ... See more keywords
SYNTHESIS AND ANTIVIRAL ACTIVITY OF NOVEL 3-SUBSTITUTED PYRAZOLINIUM SALTS
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DOI: 10.1007/6071
Abstract: For the first time, convenient methods for the preparation of pyrazoline N-alkylidene salts based on terpene (camphor, camphorquinone, carvone) ketones, cage (adamantanone and norcamphor) ketones, and natural aldehydes (carvone and myrtenal) allowing the isolation of… read more here.
Keywords: activity novel; antiviral activity; pyrazolinium salts; activity ... See more keywords
Tailoring acyclovir prodrugs with enhanced antiviral activity: rational design, synthesis, human plasma stability and in vitro evaluation
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DOI: 10.1007/s00726-018-2590-y
Abstract: Bile acid prodrugs have served as a viable strategy for refining the pharmaceutical profile of parent drugs through utilizing bile acid transporters. A series of three ester prodrugs of the antiherpetic drug acyclovir (ACV) with… read more here.
Keywords: acv; hsv; plasma stability; antiviral activity ... See more keywords
Antiviral activity of Cynodon dactylon on white spot syndrome virus (WSSV)-infected shrimp: an attempt to mitigate risk in shrimp farming
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DOI: 10.1007/s10499-020-00553-w
Abstract: White spot syndrome virus (WSSV) is the most contagious pathogen causing huge economic losses in the shrimp industry worldwide. Several medicinal plants are known to have antiviral activity through the inhibition of viral diseases in… read more here.
Keywords: dactylon; white spot; antiviral activity; spot syndrome ... See more keywords
Synthesis of cyclic D-(+)-camphoric acid imides and study of their antiviral activity
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DOI: 10.1007/s10593-020-02728-y
Abstract: Several D-(+)-camphoric acid imides, not previously described in the literature, were synthesized with good yields. The synthesis of previously known imides was improved. The cytotoxicity and antiviral activity of all synthesized imides were studied. read more here.
Keywords: antiviral activity; synthesis cyclic; camphoric acid; acid imides ... See more keywords
Methods of Synthesis and Antiviral Activity of New 4-Alkyl-3-Nitro-1,4-Dihydroazolo[5,1-c][1,2,4]Triazin-4-ols
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DOI: 10.1007/s10593-021-02926-2
Abstract: An azo coupling reaction of α-nitro ketones with 5-diazoazoles was used to obtain 4-alkyl-3-nitro-1,4-dihydroazolo[5,1- с ][1,2,4]triazines, which were characterized with respect to their antiviral activity against influenza and Coxsackie B3 viruses. read more here.
Keywords: antiviral activity; alkyl nitro; methods synthesis; nitro dihydroazolo ... See more keywords
Synthesis and antiviral activity of 1-hydroxy-2-(2-hydroxyphenyl)imidazoles against vaccinia virus
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DOI: 10.1007/s11172-019-2467-6
Abstract: Abstract2-(2-Hydroxyplienyl)imidazole derivatives were synthesized and tested for antiviral activity against vaccinia virus in Vero cell culture. 1-Methylimidazole 3-oxides, 1-methoxyimidazoles, and 1H-imidazoles showed no activity, whereas some 1-hydroxyimidazole derivatives hold promise, exhibiting antiviral activity and weak… read more here.
Keywords: activity hydroxy; antiviral activity; vaccinia virus; hydroxy hydroxyphenyl ... See more keywords