Screening and evaluation of antiviral compounds against Equid alpha-herpesviruses using an impedance-based cellular assay.
Sign Up to like & getrecommendations! Published in 2019 at "Virology"
DOI: 10.1016/j.virol.2018.10.013
Abstract: Equid alpha-herpesviruses (EHV) are responsible for different diseases in equine population. EHV-1 causes respiratory diseases, abortions and nervous disorders, EHV-4 causes respiratory diseases and sporadic abortion, while EHV-3 is responsible of equine coital exanthema. In… read more here.
Keywords: alpha herpesviruses; screening evaluation; compounds equid; antiviral compounds ... See more keywords
Multicomponent reactions in the synthesis of antiviral compounds.
Sign Up to like & getrecommendations! Published in 2021 at "Current medicinal chemistry"
DOI: 10.2174/0929867328666211007121837
Abstract: BACKGROUND Multicomponent reactions are one-pot processes for the synthesis of highly functionalized hetero-cyclic and hetero-acyclic compounds, often endowed with biological activity. OBJECTIVE Multicomponent reactions are considered green processes with high atom economy. In addition, they… read more here.
Keywords: multicomponent reactions; reactions synthesis; chemistry; antiviral compounds ... See more keywords
Investigating Multi-Target Antiviral Compounds by Screening of Phytochemicals From Neem (Azadirachta indica) Against PRRSV: A Vetinformatics Approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.854528
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) is a global health problem for pigs. PRRSV is highly destructive and responsible for significant losses to the swine industry. Vaccines are available but incapable of providing adequate… read more here.
Keywords: antiviral compounds; target antiviral; multi target; prrsv ... See more keywords
Plants as Biofactories for Therapeutic Proteins and Antiviral Compounds to Combat COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13030617
Abstract: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had a profound impact on the world’s health and economy. Although the end of the pandemic may come in… read more here.
Keywords: combat covid; plants biofactories; biofactories therapeutic; covid ... See more keywords
Discovery of Potential Antiviral Compounds against Hendra Virus by Targeting Its Receptor-Binding Protein (G) Using Computational Approaches
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020554
Abstract: Hendra virus (HeV) belongs to the paramyxoviridae family of viruses which is associated with the respiratory distress, neurological illness, and potential fatality of the affected individuals. So far, no competitive approved therapeutic substance is available… read more here.
Keywords: discovery potential; antiviral compounds; hendra virus; receptor ... See more keywords
Machine Learning for the Prediction of Antiviral Compounds Targeting Avian Influenza A/H9N2 Viral Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Symmetry"
DOI: 10.3390/sym14061114
Abstract: Avian influenza subtype A/H9N2—which infects chickens, reducing egg production by up to 80%—may be transmissible to humans. In humans, this virus is very harmful since it attacks the respiratory system and reproductive tract, replicating in… read more here.
Keywords: machine; machine learning; avian influenza; antiviral compounds ... See more keywords