Association of antiviral drugs and their possible mechanisms with DRESS syndrome using data mining algorithms
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28671
Abstract: Antiviral drugs are not known for drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. The current study aims is to find out the association of antiviral drugs and their possible mechanism with DRESS. Data… read more here.
Keywords: mining algorithms; dress syndrome; association antiviral; drugs possible ... See more keywords
Nirmatrelvir–ritonavir compared with other antiviral drugs for the treatment of COVID‐19 patients: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28732
Abstract: At present, there are some differences in the research results of nirmatrelvir–ritonavir compared with other antiviral drugs for the treatment of COVID‐19 patients. We aimed to evaluate the efficacy and safety of nirmatrelvir–ritonavir compared with… read more here.
Keywords: covid patients; compared antiviral; ritonavir compared; nirmatrelvir ritonavir ... See more keywords
Investigational antiviral drugs for the treatment of COVID-19 patients.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of virology"
DOI: 10.1007/s00705-022-05368-z
Abstract: In the current pandemic of coronavirus disease 2019 (COVID-19), antiviral drugs are at the center of attention because of their critical role against severe acute respiratory disease syndrome coronavirus 2 (SARS-CoV-2). In addition to designing… read more here.
Keywords: investigational antiviral; drugs treatment; antiviral drugs; covid ... See more keywords
Innovation and trends in the development and approval of antiviral medicines: 1987–2017 and beyond
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.05.005
Abstract: ABSTRACT 2017 marked the 30th anniversary of the approval of zidovudine (AZT) as the first HIV/AIDS therapy. Since then, more than eighty antiviral drugs have received FDA approval, half of which treat HIV infection. Here,… read more here.
Keywords: research; antiviral drugs; antiviral medicines; approved antiviral ... See more keywords
Antiviral drug screening by assessing epithelial functions and innate immune responses in human 3D airway epithelium model
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DOI: 10.1016/j.antiviral.2018.06.007
Abstract: ABSTRACT Respiratory viral infections cause mild to severe diseases, such as common cold, bronchiolitis and pneumonia and are associated with substantial burden for society. To test new molecules for shortening, alleviating the diseases or to… read more here.
Keywords: epithelial functions; antiviral drug; antiviral drugs; mucociliary clearance ... See more keywords
The study of antiviral drugs targeting SARS-CoV-2 nucleocapsid and spike proteins through large-scale compound repurposing
Sign Up to like & getrecommendations! Published in 2021 at "Heliyon"
DOI: 10.1016/j.heliyon.2021.e06387
Abstract: Contributing to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clinical treatment, a drug library encompassing approximately 3,142 clinical-stage or FDA-approved small molecules is profiled to identify the candidate therapeutic inhibitors targeting nucleocapsid protein (N) and… read more here.
Keywords: protein; domain protein; drugs targeting; antiviral drugs ... See more keywords
Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Infection and Public Health"
DOI: 10.1016/j.jiph.2020.10.015
Abstract: Background Outbreak of COVID-19 has been recognized as a global health concern since it causes high rates of morbidity and mortality. No specific antiviral drugs are available for the treatment of COVID-19 till date. Drug… read more here.
Keywords: rna; antiviral drugs; drug; indinavir tipranavir ... See more keywords
Current antiviral drugs and their analysis in biological materials—Part I: Antivirals against respiratory and herpes viruses
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.06.071
Abstract: HighlightsRole of antivirals in current pharmacotherapy is summarized; viruses that can be medically suppressed are listed.Current bioanalytical methods are presented.Mechanisms of action and therapeutic use of antivirals against herpes viruses and respiratory viruses are outlined.Analytical… read more here.
Keywords: antivirals respiratory; respiratory herpes; part; analysis ... See more keywords
Cytomegalovirus and other herpesviruses after hematopoietic cell and solid organ transplantation: From antiviral drugs to virus-specific T cells.
Sign Up to like & getrecommendations! Published in 2022 at "Transplant immunology"
DOI: 10.1016/j.trim.2022.101539
Abstract: Herpesviruses can either cause primary infection or may get reactivated after both hematopoietic cell and solid organ transplantations. In general, viral infections increase post-transplant morbidity and mortality. Prophylactic, preemptive, or therapeutically administered antiviral drugs may… read more here.
Keywords: antiviral drugs; solid organ; virus specific; specific cells ... See more keywords
Occurrence, removal and mass loads of antiviral drugs in seven wastewater treatment plants with various treatment processes.
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DOI: 10.1016/j.watres.2021.117803
Abstract: Antiviral drugs are among the most common and important classes of pharmaceuticals to treat viral infections, however their continuous emission and persistence in the receiving environment has attracted increasing attention about their potential ecological risks.… read more here.
Keywords: treatment; treatment plants; antiviral drugs; treatment processes ... See more keywords
Controlled Protein Activities with Viral Proteases, Antiviral Peptides, and Antiviral Drugs.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical biology"
DOI: 10.1021/acschembio.3c00138
Abstract: Chemical control of protein activity is a powerful tool for scientific study, synthetic biology, and cell therapy; however, for broad use, effective chemical inducer systems must minimally crosstalk with endogenous processes and exhibit desirable drug… read more here.
Keywords: antiviral peptides; controlled protein; activity; antiviral drugs ... See more keywords