FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3–TBK1–IRF3 complex
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28655
Abstract: As the key component of host innate antiviral immunity, type I interferons (IFN‐Is) exert multiple antiviral effects by inducing hundreds of IFN‐stimulated genes. However, the precise mechanism involved in host sensing of IFN‐I signaling priming… read more here.
Keywords: tbk1; ifn signaling; traf3; tbk1 irf3 ... See more keywords
Antibacterial, antifungal, and antiviral effects of three essential oil blends
Sign Up to like & getrecommendations! Published in 2017 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.459
Abstract: New agents that are effective against common pathogens are needed particularly for those resistant to conventional antimicrobial agents. Essential oils (EOs) are known for their antimicrobial activity. Using the broth microdilution method, we showed that… read more here.
Keywords: antibacterial antifungal; essential oil; antiviral effects; effects three ... See more keywords
Antiviral effects of selected nucleoside analogues against human parechoviruses A1 and A3.
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2018.12.009
Abstract: Parechoviruses A (HPeV, Picornaviridae) are neglected human pathogens that cause sepsis-like illness and severe neurological complications in infants. There are no antivirals available for the treatment of HPeV infections. We here report on cell-based assays… read more here.
Keywords: antiviral effects; effects selected; analogues human; selected nucleoside ... See more keywords
Antiviral effects of deoxynojirimycin (DNJ)-based iminosugars in dengue virus-infected primary dendritic cells.
Sign Up to like & getrecommendations! Published in 2022 at "Antiviral research"
DOI: 10.1016/j.antiviral.2022.105269
Abstract: Dendritic cells (DCs) are important targets for dengue virus (DENV) infection and play a significant role in the early immune response. Antiviral effects of iminosugars against DENV in primary cells have been demonstrated previously in… read more here.
Keywords: antiviral effects; dnj; dendritic cells; infected primary ... See more keywords
Photocatalytic nanoparticles - From membrane interactions to antimicrobial and antiviral effects.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in colloid and interface science"
DOI: 10.1016/j.cis.2021.102526
Abstract: As a result of increasing resistance among pathogens against antibiotics and anti-viral therapeutics, nanomaterials are attracting current interest as antimicrobial agents. Such materials offer triggered functionalities to combat challenging infections, based on either direct membrane… read more here.
Keywords: photocatalytic nanoparticles; antiviral effects; antimicrobial antiviral; interactions antimicrobial ... See more keywords
Antiviral effects of human milk oligosaccharides: A review
Sign Up to like & getrecommendations! Published in 2020 at "International Dairy Journal"
DOI: 10.1016/j.idairyj.2020.104784
Abstract: Abstract Virus infections can threaten human life and health and often cause considerable losses to society. There are multiple ways for viruses to invade host cells. Therefore, it is immensely important to inhibit the contact… read more here.
Keywords: antiviral effects; milk oligosaccharides; human milk; effects human ... See more keywords
Virucidal and antiviral effects of Thymus vulgaris essential oil on feline coronavirus
Sign Up to like & getrecommendations! Published in 2021 at "Research in Veterinary Science"
DOI: 10.1016/j.rvsc.2021.04.024
Abstract: Feline infectious peritonitis (FIP) is a fatal systemic disease of felids caused by a Coronavirus (CoV) (FIPV). In spite of its clinical relevance and impact on feline health, currently the therapeutic possibilities for treatment of… read more here.
Keywords: thymus vulgaris; antiviral effects; coronavirus; feline ... See more keywords
Microbiota-independent antiviral effects of antibiotics on poliovirus and coxsackievirus.
Sign Up to like & getrecommendations! Published in 2020 at "Virology"
DOI: 10.1016/j.virol.2020.04.001
Abstract: Coxsackieviruses primarily infect the gastrointestinal tract of humans, but they can disseminate systemically and cause severe disease. Using antibiotic treatment regimens to deplete intestinal microbes in mice, several groups have shown that bacteria promote oral… read more here.
Keywords: independent antiviral; antiviral effects; infection; antibiotic treatment ... See more keywords
Leflunomide: Traditional immunosuppressant with concurrent antiviral effects
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14491
Abstract: Leflunomide is a classic disease‐modifying anti‐rheumatic drug that is widely used to treat autoimmune diseases. Studies also show its antiviral effects in in vitro and/or in vivo experiments. Considering glucocorticoids, immunosuppressants and newly emerged antibodies… read more here.
Keywords: immunosuppressant concurrent; concurrent antiviral; infection; traditional immunosuppressant ... See more keywords
Expression of Ifnlr1 on Intestinal Epithelial Cells Is Critical to the Antiviral Effects of Interferon Lambda against Norovirus and Reovirus
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.02079-16
Abstract: ABSTRACT Lambda interferon (IFN-λ) has potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavirus, in both preventing and curing infection. Because the intestine includes a diverse array of cell types, however, the… read more here.
Keywords: antiviral effects; norovirus; ifn; expression ... See more keywords
Human Type I Interferon Antiviral Effects in Respiratory and Reemerging Viral Infections
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/1372494
Abstract: Type I interferons (IFN-I) are a group of related proteins that help regulate the activity of the immune system and play a key role in host defense against viral infections. Upon infection, the IFN-I are… read more here.
Keywords: type interferon; antiviral effects; human type; viral infections ... See more keywords