Human Cervical Epithelial Cells Release Antiviral Factors and Inhibit HIV Replication in Macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Innate Immunity"
DOI: 10.1159/000490586
Abstract: The female reproductive tract is a major site of HIV sexual transmission. We here examined whether human cervical epithelial cells (HCEs) can be immunologically activated and produce antiviral factors against HIV. We demonstrated that HCEs… read more here.
Keywords: epithelial cells; human cervical; cervical epithelial; hiv ... See more keywords
Human Intestinal Epithelial Cells Release Antiviral Factors That Inhibit HIV Infection of Macrophages
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00247
Abstract: As a rich source of CD4+ T cells and macrophages, the gastrointestinal (GI) tract is a major target site for HIV infection. The interplay between GI-resident macrophages and intestinal epithelial cells (IECs) constitutes an important… read more here.
Keywords: hiv infection; epithelial cells; intestinal epithelial; factors inhibit ... See more keywords
Comprehensive Transcriptomic Analysis Identifies Novel Antiviral Factors Against Influenza A Virus Infection
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.632798
Abstract: Influenza A virus (IAV) has a higher genetic variation, leading to the poor efficiency of traditional vaccine and antiviral strategies targeting viral proteins. Therefore, developing broad-spectrum antiviral treatments is particularly important. Host responses to IAV… read more here.
Keywords: epithelial cells; infection; antiviral factors; influenza virus ... See more keywords
Modulation of HIV Replication in Monocyte-Derived Macrophages (MDM) by Host Antiviral Factors Secretory Leukocyte Protease Inhibitor and Serpin Family C Member 1 Induced by Steroid Hormones
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14010095
Abstract: The impact of steroid hormones estrogen and progesterone on human immunodeficiency virus type 1 (HIV-1) replication is well documented. However, the exact mechanism involved in the regulation of HIV-1 replication by estrogen and progesterone is… read more here.
Keywords: host antiviral; hiv replication; hiv; protease inhibitor ... See more keywords
Two PARP13 isoforms are associated with induction of antiviral factors in oral mucosal cells.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular medicine reports"
DOI: 10.3892/mmr.2022.12622
Abstract: Innate immune systems in the oral cavity have important roles in the host defense against viral invasion of oral mucosa. Poly(ADP‑ribose) polymerase 13 (PARP13), which has a strong antiviral ability, has been reported to possess two isoforms;… read more here.
Keywords: expression; zapl zaps; oral mucosal; poly ... See more keywords